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The misfolding of proteins leads to numerous diseases including Akzheimer’s, Parkinson’s and Type II Diabetes. Understanding of exactly how proteins fold is crucial for many medical advancements. Chenna and Englander addressed this problem by measuring the rate of hydrogen-deuterium exchange within proteins exposed to deuterium oxide in order to further elucidate the process of protein folding. Here, mass spectrometry was used to measure exchange in Cytochrome c and was compared to archived 1H NMR data.

In this article the authors investigate whether there is a correlation between age of a person and their outlook on global issues such as technology, politics, and environment. They find a correlation between increased age and decreased optimism. However regardless of age, they find that respondents believe certain characteristics such as technology and willingness to change are essential for improvements.

In this study, Imani et al. investigate whether a new proprietary herbal formulation, HF1, can inhibit expression of immune suppressor protein PD-L1. PD-L1 is a transmembrane protein that can be expressed by cancer cells to assist in their ability to avoid attacks from the immune system. Work from this study demonstrates that HF1 treatment can reduce expression of PD-L1 in cultured cancer cells, implicating HF1 as a potential new cancer therapy.

Unprocessed water from hand-pressed wells is still commonly used as a source of drinking water in Chenzhou, the “Nonferrous Metal Village” of China. Long et al. conducted a study to measure the heavy metal contamination levels and potential health effects in this area. Water samples were analyzed through Inductively Coupled Plasma Optical Emission Spectroscopy (ICPOES) and the concentrations of 20 metal elements. Results showed that although none of the samples had dangerous levels of heavy metals, the concentrations of Al, Fe, and Mn in many locations substantially exceeded those suggested in the Chinese Drinking Water Standard and the maximum contaminant levels of Environmental Protection Agency (EPA). The authors have made an important discovery regarding the water safety in HuNan and their suggestions to install water treatment systems would greatly benefit the community.

The authors investigate the negative effects stress has on teen mental and physical health. Through a survey, they give Virginia teens a voice in revising the Health and Physical Education curriculum to include a standards of learning (SOL). Notably they identify factors contributing to stress levels including homework level, amount of free and sleep time, parental pressure and family encouragement.

Zebra mussels are an aquatic invasive species. They attach to essential industrial structures and harm the native ecosystem, costing millions of dollars each year to control. This study explored the effectiveness of two nontoxic materials (Sharklet & Netminder) in combating zebra mussel attachment.

Catalase is a biocatalyst used to break down toxic hydrogen peroxide into water and oxygen in industries such as cheese and textiles. Improving the efficiency of catalase would help us to make some industrial products, such as cheese, less expensively. The best way to maintain catalase’s conformation, and thus enhance its activity, is to immobilize it. The primary goal of this study was to find a new way of immobilizing catalase.

In this study, the authors investigated the biological mechanism underlying the actions of a traditional medicinal plant, Astragalus membranaceus. Using C. elegans as an experimental model, they tested the effects of AM root on heat stress responses. Their results suggest that AM root extract may enhance the activity of endogenous pathways that mediate cellular responses to heat stress.

Vibrio fischeri is an amazing species of bacteria that lives symbiotically in the light organ of luminescent bobtail squid. In this study, authors study the strength and optimal conditions for V. fischeri light production, and assess whether this luminescence could be a natural light source comparable to manmade lighting.

The "Uncanny Valley" is a phenomenon in which humans feel discomfort in the presence of objects that are almost, but not quite, human-like. In this study, the authors tested whether this phenomenon could be overcome by sharing a stressful experience with a humanoid robot. They found that human subjects more readily accepted a robot partner that they had previously shared a stressful experience with, suggesting a potential method for increasing the effectiveness of beneficial human-robot interactions by reducing the Uncanny Valley effect.