The authors looked at 5-FU resistant HeLa cells and the ability of an herbal extract to show anti-inflammatory properties.
Read More...The anticancer and anti-inflammatory effects of polyherbal drug AS20 on HeLa cells resistant to 5-Fluorouracil
The authors looked at 5-FU resistant HeLa cells and the ability of an herbal extract to show anti-inflammatory properties.
Read More...Uncovering mirror neurons’ molecular identity by single cell transcriptomics and microarray analysis
In this study, the authors use bioinformatic approaches to characterize the mirror neurons, which are active when performing and seeing certain actions. They also investigated whether mirror neuron impairment was connected to neural degenerative diseases and psychiatric disorders.
Read More...Down-regulation of CD44 inhibits Wnt/β-catenin mediated cancer cell migration and invasion in gastric cancer
In this study, we aimed to characterize CD44-mediated regulation of the Wnt/β-catenin signaling pathway, which promotes cancer invasion and metastasis. We hypothesized that CD44 down-regulation will inhibit gastric cancer cell migration and invasion by leading to down-regulation of Wnt/β-catenin signaling. We found that CD44 up-regulation was significantly related to poor prognosis in gastric cancer patients. We demonstrated the CD44 down-regulation decreased β-catenin protein expression level. Our results suggest that CD44 down-regulation inhibits cell migration and invasion by down-regulating β-catenin expression level.
Read More...Reducing PMA-induced COX-2 expression using a herbal formulation in MCF-7 breast cancer cells
In this study, the authors investigate the effect of a herbal formulation on Cyclooxygenase-2 (COX-2) expression in cancer cells. High levels of COX-2 correlates with worsened cancer outcomes and the authors hypothesize that the formulation will inhibit COX-2 levels.
Read More...The Protective Effects of Panax notoginseng Saponin on the Blood-Brain Barrier via the Nrf2/ARE Pathway in bEnd3 Cells
Disruption of the blood-brain barrier (BBB) is related to many neurological disorders, and can be caused by oxidative stress to cerebral microvascular endothelial cells (CMECs) composing the BBB. The authors of the paper investigated the protective effects of the total saponins in the leaves of Panax notoginseng (LPNS) on oxidative-stress-induced damage in a mouse cerebral microvascular endothelial cell line.
Read More...The effects of food type on mediator-less microbial fuel cell electricity output
The authors look at how different food types impact the ability of bacteria to produce electricity.
Read More...Integrating microbial fuel cell with sedum green roof for stormwater retention and renewable energy generation
The authors looked at renewable energy generators and the ability to utilize green roofs as a solution to climate change.
Read More...Comparing the Effectiveness of Popular Treatments for Swelling and Scarring
Numerous specialty treatments claim to reduce swelling and scarring; however, it is unknown if these treatments are more effective than less expensive treatments. In an attempt to determine if one outperforms the other, treatments were applied to the same subject following bilateral orthopedic foot surgery. No difference was found the specialty treatments compared to more cost-effective treatments.
Read More...Cytotoxicity evaluation of Amaranthus extracts compared with AS20 on MCF-7 cancer cells
The authors test the antiproliferative and apoptosis-inducing properties of an extract created from a traditional Indian medicinal plant of the Amaranthus genus.
Read More...A Novel Approach to Prevent and Restrict Early Stages of Cancer Cell Growth Using a Combination of Moringa and Sesame in a Drosophila Model
Sesame (Sesamum indicum) and moringa (Moringa oleifera) have natural antioxidants that could prevent cancer growth. Previously, this group found that sesame and moringa individually suppress eye tumor grown in the Drosophila melanogaster model. In the present study, combinations of sesame and moringa at different concentrations were included in the D. melanogaster diet. The impact on eye tumor development was assessed at different stages of growth.
Read More...Search articles by title, author name, or tags