The authors test the effectiveness of various cleaning agents on refrigerator shelves.
Read More...Effects of cleaning agents on bacterial growth on refrigerator surfaces
The authors test the effectiveness of various cleaning agents on refrigerator shelves.
Read More...Structure-activity relationship of berberine and G4 DNA reveals aromaticity’s effect on binding affinity
Berberine is a natural quaternary alkaloid that has anti-microbial and anti-cancer effects. This compound can bind to Guanine Quadruplex (G4) DNA secondary complexes to help inhibit cancer cell proliferation. In this study, the authors investigate whether incorporating large aromatic rings helps to stabilize berberine-G4 interactions.
Read More...Fractals: Exploring Mandelbrot Coordinates and qualitative characteristics of the corresponding Julia Set
Here based on an interest in fractals, the authors used a Julia Set Generator to consider a specific point on the Mandelbrot set with an associated coordinate. In this manner, they found that the complexity of the Mandelbrot and Julia Sets are governed by relatively simple rules, revealing that the intricate patterns of fractals can be defined by defined by simple rules and patterns.
Read More...Are alkaline spices the future of antibiotics?
The authors experimented with several commonly available alkaline spices (turmeric, cayenne pepper, and cinnamon) to study their antimicrobial properties, hypothesizing that alkaline spices would have antimicrobial activity. Results showed a zone of inhibition of bacterial growth, with the largest zone of inhibition being around turmeric, followed by cayenne pepper, and the smallest around cinnamon. These results are impactful, as common alkaline spices generally do show antibacterial properties and both bacteriostatic and bactericidal effects correlated with degree of alkalinity.
Read More...Validation of impact-absorbing football helmet facemask for head injury prevention with simulation
Head injuries are common in American football and the facemasks found on football helmets receive a lot of impact during contacts. This study investigates how effective they are at reducing concussion risk.
Read More...Determining surface tension of various liquids and shear modulus of paper using crumpling effect
In this article, the authors investigate the shear modulus of different types of paper in the setting of the crumpling effect.
Read More...Investigating Hydrogen as a Potential Alternative to Kerosene in Fueling Commercial Aircraft
Growing climate concerns have intensified research into zero-emission transportation fuels, notably hydrogen. Hydrogen is considered a clean fuel because its only major by-product is water. This project analyzes how hydrogen compares to kerosene as a commercial aircraft fuel with respect to cost, CO2 emissions, and flight range.
Read More...Racemic serine is less soluble than pure enantiomers due to stronger intermolecular hydrogen bonds
Seeking to develop a better understanding of the chemical and physical properties of amino acids that compose proteins, here the authors investigated the unusual relative insolubility of racemic mixtures of D- and L-serine compared to the solubility of pure D- or L-serine. The authors used a combination of microscopy and temperature measurements alongside previous X-ray diffraction studies to conclude that racemic DL-serine crystals consist of comparatively stronger hydrogen bond interactions compared to crystals of pure enantiomers. These stronger interactions were found to result in the unique release of heat during the crystallization of racemic mixtures.
Read More...Machine learning on crowd-sourced data to highlight coral disease
Triggered largely by the warming and pollution of oceans, corals are experiencing bleaching and a variety of diseases caused by the spread of bacteria, fungi, and viruses. Identification of bleached/diseased corals enables implementation of measures to halt or retard disease. Benthic cover analysis, a standard metric used in large databases to assess live coral cover, as a standalone measure of reef health is insufficient for identification of coral bleaching/disease. Proposed herein is a solution that couples machine learning with crowd-sourced data – images from government archives, citizen science projects, and personal images collected by tourists – to build a model capable of identifying healthy, bleached, and/or diseased coral.
Read More...Synthesis of a novel CCR1 antagonist for treatment of glioblastoma
Glioblastoma is a brain cancer caused by the presence of a fast-growing, malignant tumor in the brain. As of now, this cancer is universally lethal due to lack of efficacious treatment options. C-C chemokine receptor 1 (CCR1) is a G-protein coupled receptor that controls chemotaxis, the movement of cells in response to chemical stimuli. This research aims to synthesize potential CCR1 antagonists by coupling carboxylic acids with a triazole core. We synthesized these compounds using a simple carboxylic acid coupling and confirmed the identity of the final compounds using nuclear magnetic resonance (NMR) spectroscopy.
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