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The authors use blood smears from individuals with sickle cell disease to correlate sickle cell frequency with the occurrence of vaso-occlusive crises.

Here the authors investigated the natural recovery of stress-induced dopamine-related gene deficits in C. elegans by measuring the expression of cat-2 (dopamine biosynthesis) and sod-2 (oxidative stress) following exposure to starvation or hydrocortisone. They found that the reversibility of sod-2 and the expression of cat-2 were highly dependent on the type and severity of the stressor, suggesting that the body's natural ability to recover from dopamine dysfunction has biological limitations.

The authors looked at ways that seizures in patients with glioblastoma could be treated using C. elegans as a model system.

The authors looked at the impact of vitamin A (retinol) on growth of S. epidermidis (most abundant bacterium on the skin) and E. coli (found in the gut microbiome, but not on the skin).

The authors looked at the ability to use graphite from pencils in anodes of lithium-anode batteries.

Here, the authors investigated the integration of large language models (LLMs) with drug target affinity predictors (DTAPs) to improve drug repurposing, demonstrating a significant increase in prediction accuracy, particularly with GPT-4, for psychotropic drugs and the sigma-1 receptor. This novel approach offers to potentially accelerate and reduce the cost of drug discovery by efficiently identifying new therapeutic uses for existing drugs.

This study analyzed patient demographics in the ophthalmology department at Indira Gandhi Medical College and Hospital (IGMCH) to assess relationships between age, sex, and eye conditions. While the overall sex distribution was equal, individual conditions varied, with cataracts and retinal disorders more common in males and conjunctival conditions slightly more prevalent in females, though none were statistically significant (p > 0.05) except for cataract patients aged 50–89 (p < 0.001). Understanding these trends can help medical facilities allocate resources more effectively for improved patient care.

Dust accumulation on solar panels can reduce electricity output by 20–50%, posing a major challenge for solar energy collection. Instead of altering panel design, we explored a simpler approach by modifying surface energy through nanotexturing, predicting that hydrophobic surfaces would repel both water and dust. This study found that treating glass and silicone surfaces with potassium hydroxide (KOH) for 13 and 10 minutes, respectively, created optimal nanotextures (445 nm for glass, 205 nm for silicone), significantly reducing dirt accumulation and improving solar energy capture.

The authors use machine learning to analyze electroencephalogram data and identify slowing patterns that can indicate undetected disorders like epilepsy or dementia

Patients with cleft palate frequently struggle with speech issues such as nasal or congested speech. Lin and Parkinson conduct a meta-analysis to determine how two common types of cleft palate repair surgery compare in terms of their effects on patient's speech.