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Testing the Effects of Resveratrol, Apigenin, and Glucosamine to Effectively Reduce Prostate Cancer Cell Proliferation, Migration Levels, and Increase Apoptosis

Yang et al. | Apr 16, 2020

Testing the Effects of Resveratrol, Apigenin, and Glucosamine to Effectively Reduce Prostate Cancer Cell Proliferation, Migration Levels, and Increase Apoptosis

The current five-year survival rate of metastasized prostate cancer is only 30% and occurs in every one in nine men. Researchers have shown that people with a type of dwarfism called Laron’s Syndrome are immune to cancer due to their low levels of insulin-like growth factor-1 (IGF-1). For this reason, experimentally modifying the level of IGF-1 could provide better insight into whether lowering the levels of IGF-1 in prostate cancer cell lines (e.g. PC-3) could be an effective treatment to reduce their rates of proliferation and migration and increase apoptosis. We selected three compounds, which researchers have shown decrease IGF-1 levels, to test and combine to determine which is the most promising.

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The Effect of School Climate and Parenting Style on Academic Achievement

Myers et al. | Dec 16, 2020

The Effect of School Climate and Parenting Style on Academic Achievement

Research suggests that less effective styles of parenting tend to negatively affect grades, and more effective styles tend to produce higher grades. In this study, the authors verify previous research and confirm such relationships in a sample of African American students in a college preparatory program. By obtaining students’ perception of their school’s climate and parent’s parenting styles by various methods, the authors determined correlated these perceptions to student grades. They found no significant relationship between school climate and academic achievement.

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Antibacterial effectiveness of turmeric against gram-positive Staphylococcus epidermidis

Cox et al. | Jan 10, 2022

Antibacterial effectiveness of turmeric against gram-positive <i>Staphylococcus epidermidis</i>

Infections caused by antibiotic resistance are a leading issue faced by the medical field. The authors studied the antibacterial effectiveness of turmeric against gram-positive Staphylococcus epidermidis using antibiotic sensitivity disks. They infused blank antibiotic sensitivity disks with a 5% concentrated solution of turmeric and placed them on agar plates inoculated with bacteria. Overall, there was no measurable ZOI surrounding the turmeric disk so the measurements for all trials were 0 cm, suggesting that turmeric at a 5% concentration is not an effective antibacterial against S. epidermidis.

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The Effects of Ultraviolet Light on Escherichia coli

Kodoth et al. | Sep 07, 2015

The Effects of Ultraviolet Light on <em>Escherichia coli</em>

In this study E. coli bacteria was exposed to small UV lights currently used in school laboratories to see the effect on colony growth. This project explores how UV radiation methods could be applied in common households to inhibit bacterial growth.

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The Protective Antioxidant Effects of Sulforaphane on Germinating Radish Seeds Treated with Hydrogen Peroxide

Dasuri et al. | Feb 19, 2021

The Protective Antioxidant Effects of Sulforaphane on Germinating Radish Seeds Treated with Hydrogen Peroxide

Free radical chain reactions result when atoms containing unpaired electrons bind with biomolecules and alter their biological functions, contributing to the progression of diseases such as atherosclerosis, cancer, and diabetes. Antioxidants, such as vitamin E and sulforaphane, are effective neutralizers of free radicals and prevent cellular damage. This present study is conducted to determine the relative effectiveness of sulforaphane against free radicals generated by hydrogen peroxide (H2O2) compared with the known antioxidant vitamin E.

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Synergistic Effects of Metformin and Captopril on C. elegans

Kadıoğlu et al. | Jul 10, 2018

Synergistic Effects of Metformin and Captopril on <em>C. elegans</em>

Kadıoğlu and Oğuzalp study the synergistic effects of Metformin and Captopril, two commonly prescribed drugs for type 2 diabetes and hypertension, respectively. Using C. elegans nematodes as a model system, the authors find that the nematodes decreased in average body length when exposed to Metformin or Captopril individually, but grew 11% in body length when both drugs were used together. Because C. elegans body size is regulated in part by the TGF-β signaling pathway, the authors suggest that synergistic effects of these two drugs may be modulating TGF-β activity, a previously uncharacterized phenomenon.

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The Effect of Different Fructose Diets on the Lifespan of C. elegans

Chen et al. | May 10, 2020

The Effect of Different Fructose Diets on the Lifespan of <em>C. elegans</em>

High-fructose diets consumed widely in modern societies predisposes to metabolic diseases such as diabetes. Using the worm C. elegans, the authors of this study investigated the effect of fructose on the worm's survival rates. They found that worms fed 15% fructose had a lower life expectancy than those on a fructose-free diet. These results suggest that, like in humans, fructose has a negative effect on worm survival, which makes them an easy, attractive model to study the effects of fructose on health.

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The Effect of Neem on Common Nosocomial Infection-Causing Organisms

Shah et al. | Jan 27, 2020

The Effect of Neem on Common Nosocomial Infection-Causing Organisms

Nosocomial infections acquired in hospitals pose a risk to patients, a risk compounded by resistant microorganisms. To combat this problem, researchers have turned to bioactive compounds from medicinal plants such as the widely used neem. In the present study, researchers sought to determine the effectiveness of different neem preparations against several hospital acquired human pathogens. Neem powder in water successfully inhibited microorganism growth making it a potential agent to combat these infections.

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Effect of Fertilizer on Water Quality of Creeks over Time

Chen et al. | May 02, 2021

Effect of Fertilizer on Water Quality of Creeks over Time

Fertilizers are commonly used to improve agricultural yield. Unfortunately, chemical fertilizers can seep into drinking water, potentially harming humans and other forms of life. Here, the authors investigate the effect of fertilizer on the water quality of Saratoga Creek over time. They find that fertilizers can alter the acidity of the creek's water, which can be harmful to aquatic species, as well as increase the levels of nitrates temporarily.

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