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Antibacterial Effects of Copper Surfaces

Mulukutla et al. | May 19, 2020

Antibacterial Effects of Copper Surfaces

This study examined the ability of copper and copper alloy surfaces to inhibit bacterial growth, which may be help prevent healthcare-associated infections. The authors exposed two non-pathogenic strains of bacteria to different metal plates for varying degrees of time and measured bacterial growth.

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Pichia kudriavzevii Yeast Exposure Increases the Asthmatic Behavior of Alveolar Epithelial Cells In Vitro

Ortega et al. | Jun 07, 2019

<em>Pichia kudriavzevii</em> Yeast Exposure Increases the Asthmatic Behavior of Alveolar Epithelial Cells <em>In Vitro</em>

Asthma affects over 334 million people worldwide and is triggered by inhalation of environmental stimuli. The authors of this study characterized the effect of exposure to common spoilage yeast, Pichia kidriavzevii on alveolar epithelial cells. A direct correlation between infection duration and asthmatic status of these cells was found, indicating the potential for this yeast to be an environmental stimulus of asthma and warranting further study.

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Homology modeling of clinically-relevant rilpivirine-resistant HIV-RT variants identifies novel rilpivirine analogs with retained binding affinity against NNRTI-resistant HIV mutations

Luk et al. | Jan 24, 2022

Homology modeling of clinically-relevant rilpivirine-resistant HIV-RT variants identifies novel rilpivirine analogs with retained binding affinity against NNRTI-resistant HIV mutations

Human immunodeficiency virus (HIV), which affects tens of millions of individuals worldwide, can lead to acquired immunodeficiency syndrome (AIDS). While there is currently no cure for HIV, the development of small molecule antiretroviral agents has greatly improved the prognosis of infected individuals, especially in developed countries. Here, the authors employ homology modeling and molecular docking towards the identification of novel rilpivirine analogs that retain high binding affinity to clinically relevant rilpivirine-resistant mutations of the HIV reverse transcriptase enzyme.

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Bacteria and Antibiotic Resistance in School Bathrooms

Ciarlet et al. | Aug 24, 2020

Bacteria and Antibiotic Resistance in School Bathrooms

Since school bathrooms are widely suspected to be unsanitary, we wanted to compare the total amount of bacteria with the amount of bacteria that had ampicillin or streptomycin resistance across different school bathrooms in the Boston area. We hypothesized that because people interact with the faucet, outdoor handle, and indoor handle of the bathroom, based on whether or not they have washed their hands, there would be differences in the quantity of the bacteria presented on these surfaces. Therefore, we predicted certain surfaces of the bathroom would be less sanitary than others.

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Characterization of antibacterial properties of common spices

Gehad et al. | Oct 03, 2020

Characterization of antibacterial properties of common spices

Bacterial infection is resurging as one of the most dangerous challenges facing the medical establishment. Americans spend about 55 to 70 billion dollars per year on antibiotics, yet these antibiotics are becoming increasingly ineffective as illness-causing bacteria gain resistance to the prescribed drugs. We tested if 11 commonly-used spices could inhibit growth of the gram-negative bacteria, E. coli, the main takeaway from these experiments is that certain spices and herbs have antibacterial effects that inhibit growth of E.coli , and these spices could show similarly promising activity towards other bacteria.

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Antibiotic Residues Detected in Commercial Cow’s Milk

Memili et al. | Mar 18, 2015

Antibiotic Residues Detected in Commercial Cow’s Milk

Antibiotics are oftentimes used to treat mastitis (infection of the mammary gland) in dairy cows. Regulations require that milk from these cows be discarded until the infection has cleared and antibiotic residues are no longer detectable in the cow's milk. These regulations are in place to protect consumers and to help prevent the rise of antibiotic resistant bacteria. In this study, the authors test milk samples from 10 milk suppliers in the Greensboro, NC to see if they contain detectable levels of antibiotic residues.

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The Prevalence of Brain-Eating Roundworm Baylisascaris procyonis in Merrick County, Nebraska

Reeves et al. | Sep 20, 2018

The Prevalence of Brain-Eating Roundworm <i>Baylisascaris procyonis</i> in Merrick County, Nebraska

The authors investigated an important parasite-host relationship between the raccoon roundworm and the raccoon to understand how parasite prevalence is affected by location. They found that the parasite infection was more prevalent in raccoons found closer to human dwellings, though the number of roundworm eggs was not significantly different. These results are important human health, since roundworm infection is lethal to humans and can be transmitted from raccoons to humans - the authors suggest that more research into this parasite and awareness of its prevalence is needed to prevent disease.

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The effects of different modes of vocalization and food consumption on the level of droplet transmission of bacteria

Wong et al. | May 10, 2021

The effects of different modes of vocalization and food consumption on the level of droplet transmission of bacteria

Microbial agents reposnsible for respiratory infections are often carried in spittle, which means they can be easily transmitted. Here, the authors investigate how likely certain activities are to spread microbes carried in spittle. They also investigate whether eating certain types of food might reduce the spread of spittle-borne bacteria too.

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The Effects of Ultraviolet Light on Escherichia coli

Kodoth et al. | Sep 07, 2015

The Effects of Ultraviolet Light on <em>Escherichia coli</em>

In this study E. coli bacteria was exposed to small UV lights currently used in school laboratories to see the effect on colony growth. This project explores how UV radiation methods could be applied in common households to inhibit bacterial growth.

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