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Rhizopus stolonifer is a mold commonly found growing on bread that can cause many negative health effects when consumed. Preservatives are the well-known answer to this problem; however, many preservatives are not naturally found in food, and some have negative health effects of their own. We focused on honey as a possible solution because of its natural origin and self-preservation ability. We hypothesized that honey would decrease the growth rate of R. stolonifer . We evaluated the honey with a zone of inhibition (ZOI) test on agar plates. Sabouraud dextrose agar was mixed with differing volumes of honey to generate concentrations between 10.0% and 30.0%. These plates were then inoculated with a solution of spores collected from the mold. The ZOI was measured to determine antifungal effectiveness. A statistically significant difference was found between the means of all concentrations except for 20.0% and 22.5%. Our findings support the hypothesis as we showed a positive correlation between the honey concentration and growth rate of mold. By using this data, progress could be made on an all-natural, honey-based preservative.

Anti-diabetic drugs like Metformin are known to increase gut permeability, and this has a negative impact on patient health. These authors hypothesized that this can be mitigated using purple sweet potato extract, which is high anthocyanin content, that feeds bacteria metabolism to decrease gut permeability.

The purpose of our study was to determine if direct administration of CXCL1/KC to cardiomyocytes causes negative changes to cell density or proliferation. This molecule has been shown to reduce inflammation in certain instances. Homocysteine models the direct effect of an inflammatory agent on cardiomyocytes. Our question was whether these molecules directly impact cell density through an interaction with the cell proliferation process. We hypothesized that cells treated with CXCL1/KC would maintain the same cell density as untreated cells. In contrast, cells treated with Homocysteine or both Homocysteine and CXCL1/KC, were expected to have a higher cell density that than that of untreated cells.

Here, the authors investigated engagement with #GMOFOODS, a hashtag on TikTok. They hypothesized that content focused on the negative effects of genetically modified organisms would receive more interaction driven by consumers. They found that the most common cateogry focused on the disadvantages of GMOs related to nutrition and health with the number of views determining if the video would be provided to users.

Algal blooms pose a threat to ecosystems, but the methods used to combat these blooms might harm more than just the algae. Halepete, Graham, and Lowe-Schmahl demonstrate negative effects of anti-algae treatments on a cyanobacterium (Spirulina major), and the water fleas (Daphnia magna) that live alongside these cyanobacteria.

Trihalomethanes, probable human carcinogens, are commonly found disinfection by-products (DBPs) in public water systems (PWS). The authors investigated the correlation between trihalomethane concentrations and socioeconomic factors in New York State, finding a negative correlation between median household income and trihalomethane concentrations. The inverse association between trihalomethanes and household income may indicate socioeconomic disparity regarding drinking water quality and the need for improved efforts to assist small- and medium-sized community water systems to lower DBP levels in New York State.

Cholesterol is a major component of neuronal cell membrane and myelin sheath. In this study, the authors either transfected Neuro 2A cells with CYP46A1 cDNA or treated the cells with 24SHC. Cells expressing CYP46A1 had significantly less viability compared to the negative control. Up to 55% reduction in cell viability was also observed in 24S-HC-treated cells. This work supports that CYP46A1 and 24S-HC could directly trigger cell death. The direct involvement of 24S-HC in cell death provides further evidence that 24S-HC can be a promising biomarker for diagnosing brain damage severity.

Acid rain has caused devastating decreases in ecosystems across the globe. To mimic the effect of acid rain on the environment, the authors analyzed the growth of gram-negative (Escherichia coli) and gram-positive (Staphylococcus epidermidis) bacteria in agar solutions with different pH levels. Results show that in a given acidic environment there was a significant decrease in bacterial growth with an increase in vinegar concentration in the agar, suggesting that bacterial growth is impacted by the pH of the environment. Therefore, increased levels of acid rain could potentially harm the ecosystem by altering bacterial growth.

Oil spills are one of the most devastating events for marine life. Finding ways to clean up oil spills without the need for harsh chemicals could help decrease the negative impact of such spills. Here the authors demonstrate that using a combination of several biodegradable substances can effectively adsorb oil in seawater in a laboratory setting. They suggest further exploring the potential of such a combination as a possible alternative to commonly-used non-biodegradable substances in oil spill management.

Here the authors investigate the effects of plastic pollutants on terrestrial life. Specifically they look at the growth of Brassica rapa and determine that phosphate levels have the most negative impact on growth.