In this study, the authors investigate the anti-cancer effects of Annona Reticulata (Ramphal or custard apple) by testing whether its extract could inhibit HeLa cell viability.
Read More...Phytochemical analysis of Annona Reticulata extract and an in-vitro study on its anti-proliferative effects
In this study, the authors investigate the anti-cancer effects of Annona Reticulata (Ramphal or custard apple) by testing whether its extract could inhibit HeLa cell viability.
Read More...Disruptions in protein-protein interactions between HTT, PRPF40B, and MECP2 are involved in Lopes-Maciel-Rodan syndrome
In an extensive study of gene mutations, and their resulting effect on protein-protein interactions, Desai and Stork found that HTT-PRPF40B-MECP2 interactions are weakened with progression of Lopes-Maciel-Rodan syndrome.
Read More...Tap water quality analysis in Ulaanbaatar City
There have been several issues concerning the water quality in Ulaanbaatar, Mongolia in the past few years. This study, we collected 28 samples from 6 districts of Ulaanbaatar to check if the water supply quality met the standards of the World Health Organization, the Environmental Protection Agency, and a Mongolian National Standard. Only three samples fully met all the requirements of the global standards. Samples in Zaisan showed higher hardness (>120 ppm) and alkalinity levels (20–200 ppm) over the other districts in the city. Overall, the results show that it is important to ensure a safe and accessible water supply in Ulaanbaatar to prevent future water quality issues.
Read More...Analyzing the effect of mycorrhizal fungi on plant communication of nutrients
The authors looked at the ability of plants to transfer phosphate between each other through mycorrhizal fungi. Specifically, they looked at whether plants with excess phosphate would transfer this nutrient to other plants that had depleted levels of phosphate.
Read More...Time-Efficient and Low-Cost Neural Network to detect plant disease on leaves and reduce food loss and waste
About 25% of the food grown never reaches consumers due to spoilage, and 11.5 billion pounds of produce from gardens are wasted every year. Current solutions involve farmers manually looking for and treating diseased crops. These methods of tending crops are neither time-efficient nor feasible. I used a convolutional neural network to identify signs of plant disease on leaves for garden owners and farmers.
Read More...Transfer Learning for Small and Different Datasets: Fine-Tuning A Pre-Trained Model Affects Performance
In this study, the authors seek to improve a machine learning algorithm used for image classification: identifying male and female images. In addition to fine-tuning the classification model, they investigate how accuracy is affected by their changes (an important task when developing and updating algorithms). To determine accuracy, a set of images is used to train the model and then a separate set of images is used for validation. They found that the validation accuracy was close to the training accuracy. This study contributes to the expanding areas of machine learning and its applications to image identification.
Read More...Does technology help or hurt learning? Evidence from middle school and high school students
Here, recognizing the vastly different opinion held regarding device usage, the authors considered the effects of technology use on middle and high school students' learning effectiveness. Using an anonymous online survey they found partial support that device use at school increases learning effectiveness, but found strong support for a negative effect of technology use at home on learning effectiveness. Based on their findings they suggest that the efficacy of technology depends on environmental context along with other important factors that need consideration.
Read More...The Development of a Highly Sensitive Home Diagnosis Kit for Group A Streptococcus Bacteria (GAS)
In this article, Mai et al. have developed a do-it-yourself kit for the detection of Strep A bacterial infections. While Strep A infections require antibiotic administration, viral infections, which can present with similar symptoms, often resolve on their own. The problem with delayed antibiotic treatment is an increasing risk of complications. Currently an accurate diagnosis requires that patients make the trip to the hospital where sensitive tests can be performed. The method described here, bundled into a commercially available kit, could help speed up the identification of such bacterial infections. When presented with symptoms of a sore throat and fever, you could just buy the kit at your local pharmacy, perform the simple yet highly accurate and sensitive test, and know whether an urgent trip to the doctor's for an antibiotic prescription is necessary. How convenient!
Read More...Evaluation of Tea Extract as an Inhibitor of Oxidative Stress in Prostate Cells
One important factor that contributes to human cancers is accumulated damage to cells' DNA due to the oxidative stress caused by free radicals. In this study, the authors investigate the effects of several different tea leaf extracts on oxidative stress in cultured human prostate cells to see if antioxidants in the tea leaves could help protect cells from this type of DNA damage. They found that all four types of tea extract (as well as direct application of the antioxidant EGCG) improved the outcomes for the cultured cells, with white tea extract having the strongest effect. This research suggests that tea extracts and the antioxidants that they contain may have applications in the treatment of the many diseases associated with cellular DNA damage, including cancer.
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