In this study, the authors investigate whether the addition of microbes from native soil enhanced the seed germination and growth of mung beans, pumpkins, and pea flower plants.
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Phospholipase A2 increases the sensitivity of doxorubicin induced cell death in 3D breast cancer cell models
Inefficient penetration of cancer drugs into the interior of the three-dimensional (3D) tumor tissue limits drugs' delivery. The authors hypothesized that the addition of phospholipase A2 (PLA2) would increase the permeability of the drug doxorubicin for efficient drug penetration. They found that 1 mM PLA2 had the highest permeability. Increased efficiency in drug delivery would allow lower concentrations of drugs to be used, minimizing damage to normal cells.
Read More...Testing HCN1 channel dysregulation in the prefrontal cortex using a novel piezoelectric silk neuromodulator
Although no comprehensive characterization of schizophrenia exists, there is a general consensus that patients have electrical dysfunction in the prefrontal cortex. The authors designed a novel piezoelectric silk-based implant and optimized electrical output through the addition of conductive materials zinc oxide (ZnO) and aluminum nitride (AlN). With further research and compatibility studies, this implant could rectify electrical misfiring in the infralimbic prefrontal cortex.
Read More...Transfer Learning for Small and Different Datasets: Fine-Tuning A Pre-Trained Model Affects Performance
In this study, the authors seek to improve a machine learning algorithm used for image classification: identifying male and female images. In addition to fine-tuning the classification model, they investigate how accuracy is affected by their changes (an important task when developing and updating algorithms). To determine accuracy, a set of images is used to train the model and then a separate set of images is used for validation. They found that the validation accuracy was close to the training accuracy. This study contributes to the expanding areas of machine learning and its applications to image identification.
Read More...Ground-based Follow-up Observations of TESS Exoplanet Candidates
The goal of this study was to further confirm, characterize, and classify LHS 3844 b, an exoplanet detected by the Transiting Exoplanet Survey Satellite (TESS). Additionally, we strove to determine the likeliness of LHS 3844 b and similar planets as qualified candidates for observation with the James Webb Space Telescope (JWST).
Read More...The Feasibility of Mixed Reality Gaming as a Tool for Physical Therapy Following a Spinal Cord Injury
Physical therapy, especially for patients with spinal cord injuries, can be a difficult and tedious experience. This can result in negative health outcomes, such as patients dropping out of physical therapy or developing additional health problems. In this study, the authors develop and test a potential solution to these challenges: a mixed reality game called Skyfarer that replaces a standard physical therapy regimen with an immersive experience that can be shared with their friends and family. The findings of this study suggest that mixed reality games such as Skyfarer could be effective alternatives to conventional physical therapy.
Read More...Gradient boosting with temporal feature extraction for modeling keystroke log data
Although there has been great progress in the field of Natural language processing (NLP) over the last few years, particularly with the development of attention-based models, less research has contributed towards modeling keystroke log data. State of the art methods handle textual data directly and while this has produced excellent results, the time complexity and resource usage are quite high for such methods. Additionally, these methods fail to incorporate the actual writing process when assessing text and instead solely focus on the content. Therefore, we proposed a framework for modeling textual data using keystroke-based features. Such methods pay attention to how a document or response was written, rather than the final text that was produced. These features are vastly different from the kind of features extracted from raw text but reveal information that is otherwise hidden. We hypothesized that pairing efficient machine learning techniques with keystroke log information should produce results comparable to transformer techniques, models which pay more or less attention to the different components of a text sequence in a far quicker time. Transformer-based methods dominate the field of NLP currently due to the strong understanding they display of natural language. We showed that models trained on keystroke log data are capable of effectively evaluating the quality of writing and do it in a significantly shorter amount of time compared to traditional methods. This is significant as it provides a necessary fast and cheap alternative to increasingly larger and slower LLMs.
Read More...Exploring differences in men’s marijuana consumption and cigarette smoking by race and citizenship status
This study examined the relationship between citizenship status, racial background, and the use of marijuana and cigarettes among males in California using data from the 2017–2018 California Health Interview Survey. Findings indicated that non-citizens and naturalized citizens were less likely to use marijuana compared to US-born citizens, while Asian and Latino males were less likely to consume marijuana than White males. Additionally, various racial groups were more likely to smoke cigarettes compared to White males, suggesting that targeted health interventions based on citizenship status and race could be beneficial.
Read More...Color photometry and light curve modeling of apparent transient 2023jri
Observing transients like supernovae, which have short-lived brightness variations, helps astronomers understand cosmic phenomena. This study analyzed transient 2023jri, hypothesizing it was a Type IIb supernova. By collecting and analyzing data over four weeks, including light and color curves, they confirmed its classification and provided additional insights into this less-studied supernova type.
Read More...Investigating Lemna minor and microorganisms for the phytoremediation of nanosilver and microplastics
The authors looked at phytoremediation, the process by which plants are used to remove pollutants from our environment, and the ability of Lemna minor to perform phytoremediation in various simulated polluted environments. The authors found that L. minor could remove pollutants from the environment and that the addition of bacteria increased this removal.
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