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The Role of Temporal Lobe Epilepsy in Cardiac Structure and Function

Choi et al. | Aug 15, 2018

The Role of Temporal Lobe Epilepsy in Cardiac Structure and Function

Cardiac autonomic and structural changes may occur in temporal lobe epilepsy patients and contribute to the risk of sudden unexpected death in epilepsy patients. Choi and colleagues reviewed clinical charts to obtain patients’ lifetime seizure count, antiepileptic drug use, and history of heart disease, followed by transthoracic echocardiogram to calculate left ventricle dimensions, ejection fraction, and left ventricle mass. By comparing epilepsy patients to control subjects, they found that epilepsy patients had thinner left ventricle walls and smaller ejection fraction, but with no significant difference in left ventricle mass.

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Testing Various Synthetic and Natural Fiber Materials for Soundproofing

Karuppiah et al. | Jun 15, 2017

Testing Various Synthetic and Natural Fiber Materials for Soundproofing

Noise pollution negatively impacts the health and behavioral routines of humans and other animals, but the production of synthetic sound-absorbing materials contributes to harmful gas emissions into the atmosphere. The authors of this paper investigated the effectiveness of environmentally-friendly, cheap natural-fiber materials, such as jute, as replacements for synthetic materials, such as gypsum and foam, in soundproofing.

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From trash to treasure: A sustainable approach to oil spill clean-up

Kathir et al. | Aug 02, 2023

From trash to treasure: A sustainable approach to oil spill clean-up

In this study the authors looked at sustainable ways to clean up oil spills that harm marine life. Using water spangle leaves and milk week the authors looked at the ability to recovery oil from both fresh and salt water and the ability to reuse the organic material to clean up spills. Their results show promise to help find a sustainable, eco-friendly way to clean up oil spills and protect marine life and habitats.

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Different volumes of acetic acid affect the oxygen production of spinach leaves during photosynthesis

Wang et al. | Feb 24, 2023

Different volumes of acetic acid affect the oxygen production of spinach leaves during photosynthesis

The burning of fossil fuels, leading to an increased amount of carbon emissions, is the main cause of acid rain. Acid rain affects the process of photosynthesis, which makes the topic valuable to investigate. Our group utilizes plants to further investigate the relationship between pH value and photosynthesis. In this experiment, our group hypothesized that rain with a lower pH will decrease the rate of photosynthesis, causing less oxygen to be produced in the reaction.

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Cell cytotoxicity and pro-apoptosis on MCF-7 cells using polyherbal formulation, MAT20

Tarigopula et al. | Feb 17, 2023

Cell cytotoxicity and pro-apoptosis on MCF-7  cells using polyherbal formulation, MAT20

The purpose of this study was to test the anti-cancer properties and pro-apoptotic effects of the polyherbal formulation MAT20 as a complementary treatment. Moringa oleifera (Moringa), Phyllanthus emblica (Amla) and Ocimum sanctum (Tulsi), these 3 herbs were used to formulate MAT20, which contain phytochemicals that are known to display anti-cancer properties. In this study, we hypothesized that MCF-7 breast cancer cells treated with MAT20 would show increased cytotoxicity compared to its individual plant extracts.

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Development of a novel machine learning platform to identify structural trends among NNRTI HIV-1 reverse transcriptase inhibitors

Ashok et al. | Jun 24, 2022

Development of a novel machine learning platform to identify structural trends among NNRTI HIV-1 reverse transcriptase inhibitors

With advancements in machine learning a large data scale, high throughput virtual screening has become a more attractive method for screening drug candidates. This study compared the accuracy of molecular descriptors from two cheminformatics Mordred and PaDEL, software libraries, in characterizing the chemo-structural composition of 53 compounds from the non-nucleoside reverse transcriptase inhibitors (NNRTI) class. The classification model built with the filtered set of descriptors from Mordred was superior to the model using PaDEL descriptors. This approach can accelerate the identification of hit compounds and improve the efficiency of the drug discovery pipeline.

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