![One-step photochemical crosslinking of native proteins is feasible in tyrosine-rich bovine serum albumin](/rails/active_storage/representations/proxy/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaHBBaThJIiwiZXhwIjpudWxsLCJwdXIiOiJibG9iX2lkIn19--7728237a89e06ede36407f3f76a86c4b0447ce88/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaDdCem9MWm05eWJXRjBTU0lJY0c1bkJqb0dSVlE2QzNKbGMybDZaVWtpRFRZd01IZzJNREErQmpzR1ZBPT0iLCJleHAiOm51bGwsInB1ciI6InZhcmlhdGlvbiJ9fQ==--33b2b080106a274a4ca568f8742d366d42f20c14/Untitled.png)
In this study, the authors develop a new hydrogel using photochemical crosslinking with bovine serum albumin and methylene blue. They find that this new hydrogel has some useful applications!
Read More...One-step photochemical crosslinking of native proteins is feasible in tyrosine-rich bovine serum albumin
In this study, the authors develop a new hydrogel using photochemical crosslinking with bovine serum albumin and methylene blue. They find that this new hydrogel has some useful applications!
Read More...Investigating the potential of zinc oxide nanoparticles and zinc ions as promising approaches to lung cancer
Here, the authors chose to investigate the efficacy of zinc oxide nanoparticles (ZnO NPs) and cisplatin or zinc ions in inducing cancer apoptosis. While both treatments were found to reduce the proliferation of lung cancer cells, the authors suggest that further studies to identify the mechanism are necessary.
Read More...Primary source of dietary protein is correlated with differences in the intestinal microbiome diversity
We know relatively little about how vegan diets and non-vegan diets compare when it comes to the gut microbiome. Gollamudi and Gollamudi tackle this challenge by investigating how changes in a participant's diet affected the diversity of their intestinal microbiome.
Read More...Racemic serine is less soluble than pure enantiomers due to stronger intermolecular hydrogen bonds
Seeking to develop a better understanding of the chemical and physical properties of amino acids that compose proteins, here the authors investigated the unusual relative insolubility of racemic mixtures of D- and L-serine compared to the solubility of pure D- or L-serine. The authors used a combination of microscopy and temperature measurements alongside previous X-ray diffraction studies to conclude that racemic DL-serine crystals consist of comparatively stronger hydrogen bond interactions compared to crystals of pure enantiomers. These stronger interactions were found to result in the unique release of heat during the crystallization of racemic mixtures.
Read More...Understanding the Mechanism of Star-Block Copolymers as Nanoreactors for Synthesis of Well-Defined Silver Nanoparticles
Here, the authors characterize how silver ions nucleate a star-block copolymer to generate nano-sized silver particles.
Read More...Investigation of unknown causes of uveal melanoma uncovers seven recurrent genetic mutations
Uveal melanoma (UM) is a rare subtype of melanoma but the most frequent primary cancer of the eye in adults. The goal of this study was to research the genetic causes of UM through a comprehensive frequency analysis of base-pair mismatches in patient genomes. Results showed a total of 130 genetic mutations, including seven recurrent mutations, with most mutations occurring in chromosomes 3 and X. Recurrent mutations varied from 8.7% to 17.39% occurrence in the UM patient sample, with all mutations identified as missense. These findings suggest that UM is a recessive heterogeneous disease with selective homozygous mutations. Notably, this study has potential wider significance because the seven genes targeted by recurrent mutations are also involved in other cancers.
Read More...Testing the Effects of Resveratrol, Apigenin, and Glucosamine to Effectively Reduce Prostate Cancer Cell Proliferation, Migration Levels, and Increase Apoptosis
The current five-year survival rate of metastasized prostate cancer is only 30% and occurs in every one in nine men. Researchers have shown that people with a type of dwarfism called Laron’s Syndrome are immune to cancer due to their low levels of insulin-like growth factor-1 (IGF-1). For this reason, experimentally modifying the level of IGF-1 could provide better insight into whether lowering the levels of IGF-1 in prostate cancer cell lines (e.g. PC-3) could be an effective treatment to reduce their rates of proliferation and migration and increase apoptosis. We selected three compounds, which researchers have shown decrease IGF-1 levels, to test and combine to determine which is the most promising.
Read More...Who is at Risk for a Spinal Fracture? – A Comparative Study of National Health and Nutrition Examination Survey Data
One common age-related health problem is the loss of bone mineral density (BMD), which can lead to a variety of negative health outcomes, including increased risk of spinal fracture. In this study, the authors investigate risk factors that may be predictive of an individual's risk of spinal fracture. Their findings provide valuable information that clinicians can use in patient evaluations.
Read More...Allelopathic Effects of Kudzu (Pueraria montana) on Seed Germination and Their Potential Use As a Natural Herbicide
Plants in the wild compete with each other for nutrients and sunlight. Kudzu is a weed that is thought to secrete compounds that inhibit the growth of other plants. Here the authors find that certain parts of kudzu plants can block the germination of clover and dandelion seeds. These experiments may lead to a weed killer that is safe and naturally derived.
Read More...Milkweed sustainability in the Sonoran Desert: A. erosa is more water-efficient compared to two other species
This study assesses the capacity for milkweed species, an important host plant for Monarch butterflies, to grow in desert environments with different water levels.
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