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Mendelian randomization reveals shared genetic landscape in autism spectrum disorder and Alzheimer's disease

Lee et al. | Nov 04, 2024

Mendelian randomization reveals shared genetic landscape in autism spectrum disorder and Alzheimer's disease

Autism Spectrum Disorder (ASD) and Alzheimer's Disease (AD) are distinct conditions, but research suggests a link, as individuals with ASD are 2.5 times more likely to develop AD. A study employing genome-wide association studies and Mendelian randomization revealed shared genetic factors, particularly in synaptic regulation pathways, that may increase the risk of AD in those with ASD. These findings provide insights into the genetic underpinnings connecting the two disorders.

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Monitoring drought using explainable statistical machine learning models

Cheung et al. | Oct 28, 2024

Monitoring drought using explainable statistical machine learning models

Droughts have a wide range of effects, from ecosystems failing and crops dying, to increased illness and decreased water quality. Drought prediction is important because it can help communities, businesses, and governments plan and prepare for these detrimental effects. This study predicts drought conditions by using predictable weather patterns in machine learning models.

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Breast cancer mammographic screening by different guidelines among women of different races/ethnicities

Wang et al. | Aug 27, 2023

Breast cancer mammographic screening by different guidelines among women of different races/ethnicities

Mammographic screening is a common diagnostic tool for breast cancer among average-risk women. The authors hypothesized that adherence rates for mammographic screening may be lower among minorities (non-Hispanic black (NHB) and Hispanic/Latino) than among non-Hispanic whites (NHW) regardless of the guideline applied. The findings support other studies’ results that different racial/ethnic and socio-demographic factors can affect screening adherence. Therefore, healthcare providers should promote breast cancer screening especially among NHW/Hispanic women and women lacking insurance coverage.

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The Effect of Poverty on Mosquito-borne Illness Across the United States

Kar et al. | Feb 25, 2021

The Effect of Poverty on Mosquito-borne Illness Across the United States

Mosquito-borne diseases are a major issue across the world, and the objective for this project was to determine the characteristics that make some communities more susceptible to these diseases than others. The authors identified and studied characteristics that make communities susceptible to mosquito-borne diseases, including water in square miles, average temperature, population, population density, and poverty rates per county. They found that the population of a county is the best indicator of the prevalence of mosquito-borne diseases.

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