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Dhar and colleagues established a Type II diabetes mellitus (T2DM) model in fruit flies, using this model to induce insulin resistance and characterize the effects Resveratrol and Pterostilbene on a number of growth and activity metrics. Resveratrol and Pterostilbene treatment notably overturned the weight gain and glucose levels. The results of this study suggest that Drosophila can be utilized as a model organism to study T2DM and novel pharmacological treatments.

This study, uses SimulATe to model changes in microbial diversity and community structure upon administering a cocktail of antibiotics versus a single antibiotic. The authors hypothesized that antibiotic cocktails, particularly those combining broad-spectrum drugs like tetracyclines and trimethoprims, would cause a more significant reduction in gut microbial diversity compared to single-drug treatments. The findings confirmed a greater loss of microbial diversity with combinatorial treatments compared to single-drug treatments. While individual antibiotics dynamically reshaped the surviving species of the microbiome, antibiotic cocktails frequently cleared all species of the gut microbiome.

The authors test the effects of pH level on different kinds of dental cement to model the long-term effects of reflux-induced stomach acid exposure.

In this study, the authors determine which house model is most resistant to high winds by building smaller prototypes that could be tested with a handheld source of wind.

In this study, the authors developed a model named DNA Sequence Embedding Network (DNA-SEnet) to classify DNA-asthma associations using their genomic patterns.

The authors looked at how pharmacokinetics changed depending on the use of an in vitro or an in vivo model.

The authors looked at the impact of different harvest and feeding treatments on Heterandria formosa over three generations as a model for changes in marine ecosystems.

The authors looked at the impacts of short-chain fatty acids on muscle fiber formation as well as insulin sensitivity using a model of mouse myoblasts.

The authors looked at whether traditional Chinese medicine remedies that target the lungs and liver would reduce inflammation in a planaria model. They found that the two active compounds they tested were able to decrease induced inflammation by 97-98%.

The authors looked at whether CBD and THC would decrease reproductive rates in a Drosophila melanogaster model. They found that CBD had a greater impact on reducing hatching rates than THC, and that THC resulted in unexpected mortalities.