Nosocomial infections acquired in hospitals pose a risk to patients, a risk compounded by resistant microorganisms. To combat this problem, researchers have turned to bioactive compounds from medicinal plants such as the widely used neem. In the present study, researchers sought to determine the effectiveness of different neem preparations against several hospital acquired human pathogens. Neem powder in water successfully inhibited microorganism growth making it a potential agent to combat these infections.
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Upregulation of the Ribosomal Pathway as a Potential Blood-Based Genetic Biomarker for Comorbid Major Depressive Disorder (MDD) and PTSD
Major Depressive Disorder (MDD), and Post-Traumatic Stress Disorder (PTSD) are two of the fastest growing comorbid diseases in the world. Using publicly available datasets from the National Institute for Biotechnology Information (NCBI), Ravi and Lee conducted a differential gene expression analysis using 184 blood samples from either control individuals or individuals with comorbid MDD and PTSD. As a result, the authors identified 253 highly differentially-expressed genes, with enrichment for proteins in the gene ontology group 'Ribosomal Pathway'. These genes may be used as blood-based biomarkers for susceptibility to MDD or PTSD, and to tailor treatments within a personalized medicine regime.
Read More...Differentiation of Waste Plastic Pyrolysis Fuels to Conventional Diesel Fuel
Plastic pollution and energy shortages are pressing issues in today’s world. The authors examined whether waste plastic pyrolysis fuels are similar to conventional diesel and, thus, a plausible alternative fuel. Results showed that waste plastic pyrolysis fuels did not match up to diesel overall, though several fuels came close in calorific value.
Read More...The Effect of the Stomatal Index on the Net Rate of Photosynthesis in the Leaves of Spinacia oleracea, Vinca minor, Rhododendron spp, Epipremnum aureum, and Hedera spp
The density of stomata, or stomatal index, in plant leaves is correlated with the plant's rate of photosynthesis, and affected by the plant's climate. In this paper, authors measure the stomatal index of five plant species to derive their rates of photosynthesis. These results could help track changes in plants' photosynthetic rates with changing climate.
Read More...The Effect of Font Type on a School’s Ink Cost
Your choice of font can impact more than style. Here the authors demonstrate that font choice can affect the amount of ink a given print-out requires. The authors estimate that a switch to Garamond font, size 12, by all teachers in his school district would save almost $21,000 annually.
Read More...The gender gap in STEM at top U.S. Universities: change over time and relationship with ranking
Authors address the gender disparity in STEM fields, examining changes in gender diversity across male-dominated undergraduate programs over 19 years at 24 top universities. Analyzing data from NCES IPEDS, it identifies STEM as persistently male-dominated but notes increasing gender diversity in many disciplines, particularly in recent years. Results indicate that higher-ranked universities in disciplines like computer science and mechanical engineering show a weak correlation with improved gender diversity, suggesting effective initiatives can mitigate the gender gap in STEM, despite ongoing challenges.
Read More...Extracellular vesicles derived from oxidatively stressed stromal cells promote cancer progression
This paper hypothesized that the tumor microenvironment mediates cancer’s response to oxidative stress by delivering extracellular vesicles to cancer cells. Breast and lung cancer cells were treated with EVs, reavealing that EVs extracted from oxidatively stressed adipocytes increased the cell proliferation of breast cancer cells. These findings present a novel way that the TME influences cancer progression.
Read More...Impact of NaCl concentration in crystalline nanocellulose for printed ionic dielectrics
The authors looked at how the addition of NaCl to crystalline nanocellulose capacitors could improve performance in transistor applications. They found that NaCl can improve performance, but that further work is needed to determine the optimal concentration used depending on the intended application.
Read More...Effects of Temperature on Hand Sanitizer Efficiency
Here, recognizing the widespread use of hand sanitizers, the authors investigated their effectiveness in relation to storage temperature. They applied hand sanitizer before and after touching a cell phone and used LB-agar plates to monitor the growth of bacteria following this process. They found that 70% ethyl-alcohol-based sanitizers are least effective at temperatures above 107.27 °F and most effective at 96.17 °F.
Read More...Decolorization of textile dyes by edible white rot fungi
As fast fashion explodes in popularity, the fashion industry remains one of the most prominent industries responsible for pollution. This pollution includes a lack of treatment for textile dyes that remain toxic or carcinogenic as they persist in wastewater. To resolve this, the authors of this study set out to determine the efficacy of using edible white rot fungi for cell-based biodegradation of textile dyes into harmless chemicals. This method takes advantage of fungi found in excess from the fungi industry, decreasing food waste while addressing textile waste in tandem.
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