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Ribosome distribution affects stalling in amino-acid starved cancer cells

Deng et al. | Jan 07, 2022

Ribosome distribution affects stalling in amino-acid starved cancer cells

In this article, the authors analyzed ribosome profiling data from amino acid-starved pancreatic cancer cells to explore whether the pattern of ribosome distribution along transcripts under normal conditions can predict the degree of ribosome stalling under stress. The authors found that ribosomes in amino acid-deprived cells stalled more along elongation-limited transcripts. By contrast, they observed no relationship between read density near start and stop and disparities between mRNA sequencing reads and ribosome profiling reads. This research identifies an important relationship between read distribution and propensity for ribosomes to stall, although more work is needed to fully understand the patterns of ribosome distribution along transcripts in ribosome profiling data.

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Genomic Signature Analysis for the Strategic Bioremediation of Polycyclic Aromatic Hydrocarbons in Mangrove Ecosystems in the Gulf of Tonkin

Dao et al. | Jun 27, 2021

Genomic Signature Analysis for the Strategic Bioremediation of Polycyclic Aromatic Hydrocarbons in Mangrove Ecosystems in the Gulf of Tonkin

Engineered bacteria that degrade oil are currently being considered as a safe option for the treatment of oil spills. For this approach to be successful, the bacteria must effectively express oil-degrading genes they uptake as part of an external genoming vehicle called a "plasmid". Using a computational approach, the authors investigate plasmid-bacterium compatibility to find pairs that ensure high levels of gene expression.

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Evaluation of Microplastics in Japanese Fish Using Visual and Chemical Dissections

Srebnik et al. | Jan 20, 2021

Evaluation of Microplastics in Japanese Fish Using Visual and Chemical Dissections

Does the overuse of plastic in Japan poses an ecological risk to marine species and their consumers? Using visual and chemical dissection, all fish in this study were found to have microplastics present in their gastrointestinal tract, including two species that are typically eaten whole in Japan. Overall, these results are concerning as previous studies have found that microplastics can carry persistent organic pollutants. It is presumed that the increasing consumption of microplastics will have negative implications on organ systems such as the liver, gut, and hormones.

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The Parent-Child Relationship During the College Planning Process

Vanden et al. | Sep 19, 2019

The Parent-Child Relationship During the College Planning Process

To explore the parent-child relationship during college planning, authors surveyed high school juniors from two private schools (boarding school vs. non-boarding parochial school). After coding, survey answers indicate students at boarding schools were found to have greater fear of parental control and disappointment, while students at non-boarding parochial schoolexpressed a greater need for parental assistance.

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The Effect of Caffeine on the Regeneration of Brown Planaria (Dugesia tigrina)

Lazorik et al. | May 10, 2019

The Effect of Caffeine on the Regeneration of Brown Planaria (<em>Dugesia tigrina</em>)

The degeneration of nerve cells in the brain can lead to pathologies such as Parkinson’s disease. It has been suggested that neurons in humans may regenerate. In this study, the effect of different doses of caffeine on regeneration was explored in the planeria model. Caffeine has been shown to enhance dopamine production, and dopamine is found in high concentrations in regenerating planeria tissues. Higher doses of caffeine accelerated planeria regeneration following decapitation, indicating a potential role for caffeine as a treatment to stimulate regeneration.

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Two Wrongs Could Make a Right: Food Waste Compost Accelerated Polystyrene Consumption of Tenebrio molitor

Fu et al. | Jul 13, 2020

Two Wrongs Could Make a Right: Food Waste Compost Accelerated Polystyrene Consumption of <em>Tenebrio molitor</em>

Expanded polystyrene (EPS) is a plastic used to make food containers and packing materials that poses a threat to the environment. Mealworms can degrade EPS, but at a slow rate. Here, researchers assessed the impact of food waste compost and oats on the speed of EPS consumption by mealworms, superworms, and waxworms. A positive correlation was found between food waste compost supplementation and EPS consumption, especially by mealworms, indicating a potential industrial application.

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