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Comparing Suturing And Stapling In Coronary Bypass Grafting Anastomosis

Levy et al. | Oct 13, 2014

Comparing Suturing And Stapling In Coronary Bypass Grafting Anastomosis

Coronary artery bypass grafts are a common technique to treat coronary heart disease. The authors compared the efficacy of suturing and stapling techniques using an artificial heart pump and silicone tubing and found that suturing, while more time and skill intensive, held pressure in the tubing better than stapling.

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Using explainable artificial intelligence to identify patient-specific breast cancer subtypes

Suresh et al. | Jan 12, 2024

Using explainable artificial intelligence to identify patient-specific breast cancer subtypes

Breast cancer is the most common cancer in women, with approximately 300,000 diagnosed with breast cancer in 2023. It ranks second in cancer-related deaths for women, after lung cancer with nearly 50,000 deaths. Scientists have identified important genetic mutations in genes like BRCA1 and BRCA2 that lead to the development of breast cancer, but previous studies were limited as they focused on specific populations. To overcome limitations, diverse populations and powerful statistical methods like genome-wide association studies and whole-genome sequencing are needed. Explainable artificial intelligence (XAI) can be used in oncology and breast cancer research to overcome these limitations of specificity as it can analyze datasets of diagnosed patients by providing interpretable explanations for identified patterns and predictions. This project aims to achieve technological and medicinal goals by using advanced algorithms to identify breast cancer subtypes for faster diagnoses. Multiple methods were utilized to develop an efficient algorithm. We hypothesized that an XAI approach would be best as it can assign scores to genes, specifically with a 90% success rate. To test that, we ran multiple trials utilizing XAI methods through the identification of class-specific and patient-specific key genes. We found that the study demonstrated a pipeline that combines multiple XAI techniques to identify potential biomarker genes for breast cancer with a 95% success rate.

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How are genetically modified foods discussed on TikTok? An analysis of #GMOFOODS

Basch et al. | Nov 20, 2023

How are genetically modified foods discussed on TikTok? An analysis of #GMOFOODS
Image credit: Camilo Jimenez

Here, the authors investigated engagement with #GMOFOODS, a hashtag on TikTok. They hypothesized that content focused on the negative effects of genetically modified organisms would receive more interaction driven by consumers. They found that the most common cateogry focused on the disadvantages of GMOs related to nutrition and health with the number of views determining if the video would be provided to users.

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Using NLP to ascertain changes in the fast-fashion industry based on UN sustainable development goals

Chadha et al. | Sep 11, 2023

Using NLP to ascertain changes in the fast-fashion industry based on UN sustainable development goals
Image credit: Prudence Earl

Here, the authors sought to evaluate the efforts of fast fashion clothing companies towards sustainability, specifically in regards to the United Nations Sustainable Development Goals. The authors used natural language processing to investigate the sustainability reports of fast fashion companies focusing on terms established by the UN. They found that the most consistently addressed areas were related to sustainable consumption/production, with a focus on health and well-being emerging during the recent pandemic.

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An explainable model for content moderation

Cao et al. | Aug 16, 2023

An explainable model for content moderation

The authors looked at the ability of machine learning algorithms to interpret language given their increasing use in moderating content on social media. Using an explainable model they were able to achieve 81% accuracy in detecting fake vs. real news based on language of posts alone.

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Analysis of complement system gene expression and outcome across the subtypes of glioma

Mudda et al. | May 17, 2023

Analysis of complement system gene expression and outcome across the subtypes of glioma
Image credit: National Cancer Institute

Here the authors sought to better understand glioma, cancer that occurs in the glial cells of the brain with gene expression profile analysis. They considered the expression of complement system genes across the transcriptional and IDH-mutational subtypes of low-grade glioma and glioblastoma. Based on their results of their differential gene expression analysis, they found that outcomes vary across different glioma subtypes, with evidence suggesting that categorization of the transcriptional subtypes could help inform treatment by providing an expectation for treatment responses.

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Socio-economic and awareness correlates of physical activity of government school children in India

Nandivada et al. | Dec 11, 2022

Socio-economic and awareness correlates of physical activity of government school children in India

Here, based on the identified importance of physical activity in the development of young children, the authors investigated the effects of socioeconomic factors on the amount of physical activity of government-school children in India. They found significant differences between boys and girls, rural and urban, and children who were encouraged to exercise and those who were not. Overall, they suggest that their findings point to the important role of schools and communities in promoting healthy active lifestyles for developing children.

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The sweetened actualities of neural membrane proteins: A computational structural analysis

Chauhan et al. | Nov 03, 2022

The sweetened actualities of neural membrane proteins: A computational structural analysis

Here, seeking to better understand the roles of glycans in the receptors of active sites of neuronal cells, the authors used molecular dynamics simulations to to uncover the dynamic nature of N-glycans on membrane proteins. The authors suggest the study of theinteractions of these membrane poreins could provide future potential therapeutic targets to treat mental diseases.

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