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The Effects of Altered Microbiome on Caenorhabditis elegans Egg Laying Behavior

Gohari et al. | Aug 12, 2019

The Effects of Altered Microbiome on <em>Caenorhabditis elegans</em> Egg Laying Behavior

Since the discovery that thousands of different bacteria colonize our gut, many of which are important for human wellbeing, understanding the significance of balancing the different species on the human body has been intensely researched. Untangling the complexity of the gut microbiome and establishing the effect of the various strains on human health is a challenge in many circumstances, and the need for simpler systems to improve our basic understanding of microbe-host interactions seems necessary. C. elegans are a well-established laboratory animal that feed on bacteria and can thus serve as a less complex system for studying microbe-host interactions. Here the authors investigate how the choice of bacterial diet affects worm fertility. The same approach could be applied to many different outcomes, and facilitate our understanding of how the microbes colonizing our guts affect various bodily functions.

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A Retrospective Study of Research Data on End Stage Renal Disease

Ponnaluri et al. | Mar 09, 2016

A Retrospective Study of Research Data on End Stage Renal Disease

End Stage Renal Disease (ESRD) is a growing health concern in the United States. The authors of this study present a study of ESRD incidence over a 32-year period, providing an in-depth look at the contributions of age, race, gender, and underlying medical factors to this disease.

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A five-year retrospective analysis of Tuberculosis risk factors and their variability in the United States

Kini et al. | Mar 14, 2026

A five-year retrospective analysis of Tuberculosis risk factors and their variability in the United States
Image credit: Kini, Diaz Gaviria, Diaz, and Kini

The main goal of this study is to determine what demographics are related to tuberculosis incidence in the United States populations, particularly if changing demographics are related to differences in tuberculosis risk over two discrete time periods. The major finding is that in the two studied time periods, tuberculosis risk factors were somewhat consistent and may be influenced by things such as immigration, healthcare access, and race or ethnicity, although the top predictor did change.

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