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Conversion of Mesenchymal Stem Cells to Cancer-Associated Fibroblasts in a Tumor Microenvironment: An in vitro Study

Ramesh et al. | Feb 18, 2020

Conversion of Mesenchymal Stem Cells to Cancer-Associated Fibroblasts in a Tumor Microenvironment: An <em>in vitro</em> Study

Mesenchymal stem cells(MSCs) play a role in tumor formation by differentiating into cancer associated fibroblasts (CAFs) which enable metastasis of tumors. The process of conversion of MSCs into CAFs is not clear. In this study, authors tested the hypothesis that cancers cells secrete soluble factors that induce differentiation by culturing bone marrow mesenchymal stem cells in media conditioned by a breast cancer cell line.

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Predicting the factors involved in orthopedic patient hospital stay

D’Souza et al. | Dec 13, 2023

Predicting the factors involved in orthopedic patient hospital stay
Image credit: Pixabay

Long hospital stays can be stressful for the patient for many reasons. We hypothesized that age would be the greatest predictor of hospital stay among patients who underwent orthopedic surgery. Through our models, we found that severity of illness was indeed the highest factor that contributed to determining patient length of stay. The other two factors that followed were the facility that the patient was staying in and the type of procedure that they underwent.

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Antibacterial properties of household spices and toothpaste against oral bacteria

Toliver et al. | Apr 24, 2023

Antibacterial properties of household spices and toothpaste against oral bacteria

Bacteria cause tooth decay, plaque, bad breath, and other diseases. Despite being cleaned with water and toothpaste, oral bacteria live on our toothbrushes. Bacterial growth has been shown to be inhibited by different toothpastes and common household spices. This study tested how different toothpastes and common household spices, including cinnamon, cumin, nutmeg, and ground white pepper, can inhibit bacteria from growing on toothbrushes

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The study of technology and the use of individual cognitive effort

Neravetla et al. | Jan 24, 2023

The study of technology and the use of individual cognitive effort
Image credit: Glenn Carstens-Peters

A trial study was performed in 2021 to investigate the link between technology and transactive memory. Transactive memory is shared knowledge in which members share the responsibility to encode, store, and retrieve certain tasks or assignments, leading to a successful and collective performance. We hypothesize that a participants’ expected access to an external source affects the recall rate and retrieval of information.

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Developing a Method to Remove Inorganic Arsenic from Rice with Natural Substances

Mukai et al. | Oct 27, 2020

Developing a Method to Remove Inorganic Arsenic from Rice with Natural Substances

In this study, the authors tested different approaches for removing arsenic from rice. Due to higher arsenic levels in water, some areas grow rice with higher levels as well. This is a health hazard and so developing methods to remove arsenic from the rice will be helpful to many. Using a rapid arsenic kit, the authors found that activated charcoal was the most effective at removing arsenic from rice.

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Phages Can Be More Effective and Specific Than Antibiotics in Combating Bacteria

Wu et al. | Feb 17, 2019

Phages Can Be More Effective and Specific Than Antibiotics in Combating Bacteria

Phage therapy has been suggested as an alternative to antibiotics because bacteria resistant to antibiotics may still be susceptible to phages. However, phages may have limited effectiveness in combating bacteria since bacteria possess several antiviral defense mechanisms and can quickly develop resistance to phages. In this study, Wu and Pinta compare the effectiveness and specificity of antibiotics and phages in combating bacteria. They found that T4 phages are more specific and effective in fighting or inhibiting both antibiotic-resistant and sensitive bacteria than antibiotics, suggesting that phage therapy can be developed as an efficient tool to combat antibiotic-resistant bacteria.

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