Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer, with early diagnosis and treatment challenges. When any of the genes KRAS, SMAD4, TP53, and BRCA2 are heavily mutated, they correlate with PDAC progression. Cellular stress, partly regulated by the gene SERPINA6, also correlates with PDAC progression. When SERPINA6 is highly expressed, corticosteroid-binding globulin inhibits the effect of the stress hormone cortisol. In this study, the authors explored whether there is an inverse correlation between the expression of SERPINA6 and PDAC-linked genes.

Malaria is a major public health issue, especially in developing countries, and vector control is a major facet of malaria eradication efforts. Recently, sterile insect technique (SIT), or the release of sterile mosquitoes into the wild, has shown significant promise as a method of keeping vector populations under control. In this study, the authors investigate the Anopheles gambiae transglutaminase 3 protein (AgT3), which is essential to the mating of the Anopheles mosquito. They show that an active site mutation is able to abolish the activity of the AgT3 enzyme and propose it as a potential target for chemosterilant inhibitors.

There are two types of competing TV screens on the market, organic light emitting diode (OLED) and liquid crystal display (LCD). The better capability to exhibit black results in higher contrast images. Here, authors compared the ability of the two types of screens to show black in an environment eliminating external light.

In this study, the authors use aerosol optical depth data to determine if aerosol levels were lower in major metropolitan areas around the world during the COVID-19 pandemic.

In this study, the authors investigate the relationship between iron/hydrogen ratio [Fe/H] of a type of variable stars commonly used as reference points RR Lyrae stars and their light curves to see if one can determine the composition of these stars solely by measuring their light curve characteristics.

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder and is difficult to diagnose in young children. Here magnetoencephalography was used to compare the brain activity in patients with ASD to patients in a control group. The results show that patients with ASD have a high level of activity in different areas of the brain than those in the control group.

Using facial recognition as a use-case scenario, we attempt to identify sources of bias in a model developed using transfer learning. To achieve this task, we developed a model based on a pre-trained facial recognition model, and scrutinized the accuracy of the model’s image classification against factors such as age, gender, and race to observe whether or not the model performed better on some demographic groups than others. By identifying the bias and finding potential sources of bias, his work contributes a unique technical perspective from the view of a small scale developer to emerging discussions of accountability and transparency in AI.

Studying exoplanets, or planets that orbit a star other than the Sun, is critical to a greater understanding the formation of planets and how Earth's solar system differs from others. In this study the authors analyze the transit light curves of three hot Jupiter exoplanets to ultimately determine if and how these planets have changed since their discovery.

Pathogenic fungi such as Alternaria alternata (A. alternata) can decimate crop yields and severely limit food supplies when left untreated. Copper chitosan (CuCts) is a promising alternative fungicide for developing agricultural areas due to being inexpensive and nontoxic. We hypothesized that LMWc CuCts would exhibit greater fungal inhibition due to the beneficial properties of LMWc.

Neural machine translation (NMT) is a software that uses neural network techniques to translate text from one language to another. However, one of the most famous NMT models—Google Translate—failed to give an accurate English translation of a famous Korean nursery rhyme, "Airplane" (비행기). The authors fine-tuned a pre-trained model first with a dataset from the lyrics domain, and then with a smaller dataset containing the rhythmical properties, to teach the model to translate rhythmically accurate lyrics. This stacked fine-tuning method resulted in an NMT model that could maintain the rhythmical characteristics of lyrics during translation while single fine-tuned models failed to do so.