Alzheimer's disease is one of the leading causes of death in the United States and is characterized by neurodegeneration. Mishra et al. wanted to understand the role of two transport proteins, LRP1 and AQP4, in the neurodegeneration of Alzheimer's disease. They used a model organism for Alzheimer's disease, the nematode C. elegans, and genetic engineering to look at whether they would see a decrease in neurodegeneration if they increased the amount of these two transport proteins. They found that the best improvements were caused by increased expression of both transport proteins, with smaller improvements when just one of the proteins is overly expressed. Their work has important implications for how we understand neurodegeneration in Alzheimer's disease and what we can do to slow or prevent the progression of the disease.

This study is centered around developing biofortification methods: the authors test whether the amount of calcium available to growing crops translates into more calcium present in the crops.

Here, recognizing a declining supply of rock phosphate, as well as its role in crop fertilization, the authors investigated a fungus that forms a symbiotic relationship with many crops. They found that symbiosis between the fungus and common bean plant increased the affinity of the plant towards absorbing nutrients as evidenced by lower root-to-shoot ratios in beans planted in soil with various concentrations of phosphorous and salinity.

The authors test the levels of reducing sugars in avocados, soybeans, and cinnamon as part of a diet for individuals managing Type II diabetes.

Plastic pollution in the ocean is a major global concern. Remotely Operated Vehicles (ROVs) have promise for removing debris from the ocean, but more research is needed to achieve full effectiveness of the ROV technology. Wahlig and Gonzales tackle this issue by developing a deep learning model to distinguish trash from the environment in ROV images.

Industrialization has transformed human life and improved it for many. Nonetheless, a side effect has been an increase in chemical waste, which when not disposed of properly, has detrimental effects on surrounding habitats. An increase in ocean acidification could potentially affect many forms of life, disrupting the ecological balance in unforeseeable ways. In this article the authors explore the effect of acidification on corals and shells, and observe that an increase in ocean acidity has a significant effect on corals, but not shells. This illustrates how acidification could negatively affect marine life, and calls our attention to managing the factors that contribute to increasing the pH of the Earth's water bodies.

The authors looked at the ability of Shewanella oneidensis to generate energy in a microbial fuel cell under varying conditions. They found that the S. Onedensis biofilm was able to produce energy in microgravity and that one of the biggest factors that limited energy production was a decrease in growth medium present.

The sugar-rich modern diet underlies a suite of metabolic disorders, most common of which is diabetes. Accurately reporting the sugar content of pre-packaged food and drink items can help consumers track their sugar intake better, facilitating more cognisant and, eventually, moderate consumption of high-sugar items. In this article, the authors examine the effect of several variables on the accuracy of Fehling's reaction, a colorimetric reaction used to estimate sugar content.

In this study, the authors investigate the effects of acidity on the survival of commercial probiotic Lovebug bacterial strains.

Pillai et al. look at whether exposure to Schistosoma mansoni, a parasitic blood fluke, has any relation to peanut allergies. They found that cockroaches exposed to an antigen found in S. mansoni eggs exhibited an allergic reaction to peanuts.