In this study, the authors identify new potential targets to treat advanced diffuse large B-cell lymphoma after treatment relapse and loss of CD19 expression.
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Utilizing the Magnus effect to produce more downforce than a standard wing
Here, seeking a better solution to produce downforce that keeps a vehicle grounded at high speeds than wings which tend to result in degraded car performance due to increased air resistance, the authors considered using the Magnus effect as a replacement. The authors found that a spinning cylinder generated significantly more downforce through the Magnus effect than a standard wing at all wind speeds as simulated through the use of a leaf blower. They suggest that a cylinder could be a potential replacement for a wing when downforce is a priority.
Read More...Testing Epoxy Strength: The High Strength Claims of Selleys’s Araldite Epoxy Glues
Understanding the techniques used to improve the adhesion strength of the epoxy resin is important especially for consumer applications such as repairing car parts, bonding aluminum sheeting, and repairing furniture or applications within the aviation or civil industry. Selleys Araldite epoxy makes specific strength claims emphasizing that the load or weight that can be supported by the adhesive is 72 kg/cm2. Nguyen and Clarke aimed to test the strength claims of Selley’s Araldite Epoxy by gluing two steel adhesion surfaces: a steel tube and bracket. Results showed that there is a lack of consideration by Selleys for adhesion loss mechanisms and environmental factors when accounting for consumer use of the product leading to disputable claims.
Read More...The Effects of Ocean Acidification on the food location behavior and Locomotion of Pagurus Longicarpus
Increasing levels of atmospheric carbon dioxide is slowly acidifying our oceans. Here the authors test the effects of ocean acidification on the ability of hermit crabs (P. longicarpus) to find food. Though no statistically significant changes in food finding were observed, the data suggest a trend toward different activity.
Read More...How has California’s Shelter-in-Place Order due to COVID-19 and the Resulting Reduction in Human Activity Affected Air and Water Quality?
As the world struggled to grapple with the emerging COVID-19 pandemic in 2020, many countries instated policies to help minimize the spread of the virus among residents. This inadvertently led to a decrease in travel, and in some cases, industrial output, two major sources of pollutants in today's world. Here, the authors investigate whether California's shelter-in-place policy was associated with a measurable decrease in water and air pollution in that state between June and July of 2020, compared to the preceeding five years. Their findings suggest that, by some metrics, air quality improved within certain areas while water quality was relatively unchanged. Overall, these findings suggest that changing human behavior can, indeed, help reduce the level of air pollutants that compromise air quality.
Read More...Wind Resistance and Automobile Shapes
Energy efficiency is becoming more important as we struggle to find better, more sustainable energy sources to power our planet; the car industry is no exception. In this article, the authors examine the effect of shape on automobile aerodynamics By finding the shape that makes cars less resistant to wind, and therefore more energy efficient, can help the automobile industry make better, more eco-friendly cars that are also cheaper to operate.
Read More...Comparative analysis of CO2 emissions of electric ride-hailing vehicles over conventional gasoline personal vehicles
While some believe that ride-hailing services offer reduced CO2 emissions compared to individual driving, studies have found that driving without passengers on ride-hailing trips or "deadheading" prevents this. Here, with a mathematical model, the authors investigated if the use of electric vehicles as ride-hailing vehicles could offer reduced CO2 emissions. They found that the improved vehicle efficiency and cleaner generation could in fact lower emissions compared to the use of personal gas vehicles.
Read More...Effectiveness of Biodegradable Plastic in Preventing Food Spoilage
Most people put little thought into the type of plastic wrap they use to store their leftovers. This study investigates the differences between biodegradable plastic wrap and non-biodegradable plastic wrap in their ability to prevent food spoilage. Does one work better than the other? Read more to find out!
Read More...Extending Einstein’s elevator thought experiment to multiple spatial dimensions at the Luxor Hotel & Casino
In this study, the authors conduct a series of experiments within an elevator traveling on an angle to determine if Einstein's Equivalency Principle and motion vector decomposition can be used to calculate the angle of inclination.
Read More...Investigating the Role of the Novel ESCRT-III Recruitment Factor CCDC11 in HIV Budding: A Potential Target for Antiviral Therapy
Acquired immunodeficiency syndrome (AIDS) is a life-threatening condition caused by the human immunodeficiency virus (HIV). In this work, Takemaru et al explored the role of Coiled-Coil Domain-Containing 11 (CCDC11) in HIV-1 budding. Their results suggest that CCDC11 is critical for efficient HIV-1 budding, potentially indicating CCDC11 a viable target for antiviral therapeutics without major side effects.
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