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Effects on Learning and Memory of a Mutation in Dα7: A D. melanogaster Homolog of Alzheimer's Related Gene for nAChR α7

Sanyal et al. | Oct 01, 2019

Effects on Learning and Memory of a Mutation in Dα7: A <em>D. melanogaster</em> Homolog of Alzheimer's Related Gene for nAChR α7

Alzheimer's disease (AD) involves the reduction of cholinergic activity due to a decrease in neuronal levels of nAChR α7. In this work, Sanyal and Cuellar-Ortiz explore the role of the nAChR α7 in learning and memory retention, using Drosophila melanogaster as a model organism. The performance of mutant flies (PΔEY6) was analyzed in locomotive and olfactory-memory retention tests in comparison to wild type (WT) flies and an Alzheimer's disease model Arc-42 (Aβ-42). Their results suggest that the lack of the D. melanogaster-nAChR causes learning, memory, and locomotion impairments, similar to those observed in Alzheimer's models Arc-42.

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Evaluating the performance of Q-learning-based AI in auctions

Liu et al. | Nov 09, 2025

Evaluating the performance of Q-learning-based AI in auctions
Image credit: Liu and Liu

Advertising platforms like Google Ads use AI to drive the algorithms used to maximize advertisers benefits. This study shows that AI does not adjust it strategy based on auction type and highlights the limitations of AI running without explicit guidance.

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Reinforcement learning in 2-D space with varying gravitational fields

Rousseau et al. | Jun 07, 2025

Reinforcement learning in 2-D space with varying gravitational fields
Image credit: NASA

In this study the authors looked at the ability to navigate planes in space between randomly placed planets. They used machine and reinforcement learning to run simulations and found that they were able to identify optimal paths for travel. In the future these techniques may allow for safer travel in unknown spaces.

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