Albuterol extends lifespan of Caenorhabditis elegans

(1) Dos Pueblos Senior High School, Goleta, California, (2) Dept. of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, Santa Barbara, California; Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, California, (3) Dept. of Ecology, Evolution, and Marine Biology, University of California Santa Barbara, Santa Barbara, California

Cover photo for Albuterol extends lifespan of <i>Caenorhabditis elegans</i>

The objective of this experiment is to determine if the medication albuterol has a positive impact on the lifespan of C. elegans. We hypothesize that if albuterol is added to the diet of C. elegans, then the lifespan of C. elegans will increase. C. elegans were separately incubated in the medication albuterol at 20 µg/ml at the start of the L1 phase of their life cycle. Then they were closely monitored and counted daily throughout the duration of their lifespan. Albuterol increased the mean lifespan of C. elegans by 4.31 ± 0.13 days, compared to the control group and increased the outer range of the C. elegans lifespan. The medication albuterol increased the lifespan of C. elegans. The method of which this occurred is still unknown. Further testing is required to deduce whether mitochondrial biogenesis was the contributing factor or esophageal function.

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c elegans medication lifespan aging