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Willingness to visit the pediatric dentist during the COVID-19 pandemic

Rossitch et al. | Mar 24, 2022

Willingness to visit the pediatric dentist during the COVID-19 pandemic

Because of the COVID-19 pandemic, people are missing important appointments because they are viewed as nonessential, possibly including children's pediatric dentist appointments. This study aims to determine how the COVID-19 pandemic has effected parents' willingness to allow children to visit pediatric dental practices and what safety measures would make them feel more comfortable visiting the dentist. The authors found a weak positive correlation between parents' unwillingness to allow their child to visit the dentist, however overall anxiety towards visiting the dentist during the pandemic was low.

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Computational Structure-Activity Relationship (SAR) of Berberine Analogs in Double-Stranded and G-Quadruplex DNA Binding Reveals Both Position and Target Dependence

Sun et al. | Dec 18, 2020

Computational Structure-Activity Relationship (SAR) of Berberine Analogs in Double-Stranded and G-Quadruplex DNA Binding Reveals Both Position and Target Dependence

Berberine, a natural product alkaloid, and its analogs have a wide range of medicinal properties, including antibacterial and anticancer effects. Here, the authors explored a library of alkyl or aryl berberine analogs to probe binding to double-stranded and G-quadruplex DNA. They determined that the nature of the substituent, the position of the substituent, and the nucleic acid target affect the free energy of binding of berberine analogs to DNA and G-quadruplex DNA, however berberine analogs did not result in net stabilization of G-quadruplex DNA.

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Converting SiO2 wafers to hydrophobic using chlorotrimethylsilane

Lee et al. | Aug 20, 2024

Converting SiO<sub>2</sub> wafers to hydrophobic using chlorotrimethylsilane

Semiconductors are the center of the fourth industrial revolution as they are key components for all electronics. Exposed wafers made of silicon (Si), which can easily oxidize, convert to silicon dioxide (SiO2). The surface of SiO2 wafers consists of many Si-OH bonds, allowing them to easily bond with water, resulting in a “wet” or hydrophilic condition. We sought to determine a way to modify the surface of SiO2 wafers to become hydrophobic to ensure safe wet cleaning.

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