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Analysis of reduction potentials to determine the most efficient metals for electrochemical cell alternatives

Carroll et al. | Jul 10, 2020

Analysis of reduction potentials to determine the most efficient metals for electrochemical cell alternatives

In this study, the authors investigate what metals make the most efficient electrochemical cells, which are batteries that use the difference in electrical potential to generate electricity. Calculations predicted that a cell made of iron and magnesium would have the highest efficiency. Construction of an electrochemical cell of iron and magnesium produced voltages close to the theoretical voltage predicted. These findings are important as work continues towards making batteries with the highest storage efficiency possible.

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A study to determine the anti-cancer and pro-apoptotic properties of Amaranthus spinosus Linn. Extract, AS20

Sharma et al. | Nov 24, 2020

A study to determine the anti-cancer and pro-apoptotic properties of Amaranthus spinosus Linn. Extract, AS20

In this study, the authors investigate whether a new compound has anti-cancer properties. Using the crude extract from the Amaranthus spinosus plant, HeLa cancer cells were assessed for cell death. Findings reveal that the extract (AS20) has cytotoxic effects on HeLa cells. Their findings introduce a new compound to potentially pursue in the hunt for novel cancer treatments.

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The effect of Omega-3 on bovine blood cells as a potential remedy for Cerebral Cavernous Malformations

Pulluru et al. | Sep 22, 2023

The effect of Omega-3 on bovine blood cells as a potential remedy for Cerebral Cavernous Malformations
Image credit: Carolien van Oijen

Here, the authors investigated if dietary Omega-3 fatty acids could reduce the potential for cerebral cavernous malformations, which are brain lesions that occur due to a genetic mutation where high membrane permeability occurs between endothelial cell junctions. In a bovine-based study where some cows were fed an Omega-3 diet, the authors found the membranes of bovine blood cells increased in thickness with Omega-3 supplementation. As a result, they suggest that dietary Omega-3 could be considered as a possible preventative measure for cerebral cavernous malformations.

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Down-regulation of CD44 inhibits Wnt/β-catenin mediated cancer cell migration and invasion in gastric cancer

Baek et al. | May 10, 2021

Down-regulation of CD44 inhibits Wnt/β-catenin mediated cancer cell migration and invasion  in gastric cancer

In this study, we aimed to characterize CD44-mediated regulation of the Wnt/β-catenin signaling pathway, which promotes cancer invasion and metastasis. We hypothesized that CD44 down-regulation will inhibit gastric cancer cell migration and invasion by leading to down-regulation of Wnt/β-catenin signaling. We found that CD44 up-regulation was significantly related to poor prognosis in gastric cancer patients. We demonstrated the CD44 down-regulation decreased β-catenin protein expression level. Our results suggest that CD44 down-regulation inhibits cell migration and invasion by down-regulating β-catenin expression level.

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Comparing the effects of electronic cigarette smoke and conventional cigarette smoke on lung cancer viability

Choe et al. | Sep 18, 2022

Comparing the effects of electronic cigarette smoke and conventional cigarette smoke on lung cancer viability

Here, recognizing the significant growth of electronic cigarettes in recent years, the authors sought to test a hypothesis that three main components of the liquid solutions used in e-cigarettes might affect lung cancer cell viability. In a study performed by exposing A549 cells, human lung cancer cells, to different types of smoke extracts, the authors found that increasing levels of nicotine resulted in improve lung cancer cell viability up until the toxicity of nicotine resulted in cell death. They conclude that these results suggest that contrary to conventional thought e-cigarettes may be more dangerous than tobacco cigarettes in certain contexts.

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