
The authors describe the design and testing of new guide RNAs targeting the DMPK gene, which is responsible for myotonic dystrophy.
Read More...Designing gRNAs to reduce the expression of the DMPK gene in patients with classic myotonic dystrophy
The authors describe the design and testing of new guide RNAs targeting the DMPK gene, which is responsible for myotonic dystrophy.
Read More...Investigating AlphaFold’s handling of nanobody-antigen complex prediction
Predicting antibody structures and antibody-antigen complexes using AlphaFold
Read More...Effects of common supplements on human platelet aggregation in vitro
There is a need for safe and effective therapies to prevent platelet aggregation associated with cardiovascular diseases. Prabhakar and Prabhakar test to see whether dietary supplements claiming to reduce cardiovascular disease risk will affect aggregation of human platelets.
Read More...Implication of education levels on gender wage gap across states in the United States and Puerto Rico
Here the authors examined the relationship between education levels and the gender wage gap (GWG) in the US and Puerto Rico from 2010 to 2022, hypothesizing that higher education would correlate with a lower GWG. Their analysis of income data revealed an inverse correlation, where higher education levels were associated with reduced gender wage disparities, suggesting that policies aimed at closing the gender gap in higher education could promote socioeconomic equality.
Read More...A comparative analysis of machine learning approaches to predict brain tumors using MRI
The authors use machine learning on MRI images of brain tissue to predict tumor onset as an avenue for early detection of brain cancer.
Read More...The Mount Laurel doctrine: A case study in housing affordability and the labor market in New Jersey
The authors explored the effects of the Mount Laurel Doctrine on housing affordability, unemployment rate, and civilian labor force in Burlington County, New Jersey compared to nearby counties.
Read More...Development of novel biodegradable bioplastics for packaging film using mango peels
Here the authors explored the development of biodegradable bioplastic films derived from mango peels as a sustainable solution to plastic pollution and greenhouse gas emissions from fruit waste. They optimized the film's mechanical properties and water resistance through adjusting processing conditions and incorporating plasticizers and a hydrophobic coating, ultimately demonstrating its potential as a bacteriostatic and biodegradable alternative to conventional plastic food wrap.
Read More...Optimizing an eDNA assay and field deployment to detect decapod species in Oʻahu streams
This study explored the use of environmental DNA (eDNA) methods to detect native Hawaiian decapod species (‘opae), which are difficult to observe manually due to their low density.
Read More...Comparative study of machine learning models for water potability prediction
The global issue of water quality has led to the use of machine learning models, like ANN and SVM, to predict water potability. However, these models can be complex and resource-intensive. This research aimed to find a simpler, more efficient model for water quality prediction.
Read More...Higher pH level increases the efficacy of calcium phosphate-mediated intracellular delivery
This study investigated the impact of pH on the efficiency of calcium phosphate, used as a drug delivery agent.
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