
The authors investigate whether human blood cancers carrying mutations in DNA repair genes possess increased sensitivity to common chemotherapy drugs cisplatin or gemcitabine.
Read More...DNA repair protein mutations alter blood cancer sensitivity to cisplatin or gemcitabine in vitro
The authors investigate whether human blood cancers carrying mutations in DNA repair genes possess increased sensitivity to common chemotherapy drugs cisplatin or gemcitabine.
Read More...The analysis of the antimicrobial benefits of Populus balsamifera
In this study, the authors investigated the antimicrobial properties of the tree species, Populus balsamifera. It was observed that the extract of the buds of P. balsamifera was highly effective against gram-positive bacteria. This helps to indicate the potential use of P. balsamifera in the medical field to eliminate gram-positive bacteria.
Read More...A novel bioreactor system to purify contaminated runoff water
In this study, the authors engineer a cost-effective and bio-friendly water purification system using limestone, denitrifying bacteria, and sulfate-reducing bacteria. They evaluated its efficacy with samples from Eastern PA industrial sites.
Read More...Developing “Off the Shelf” Pancreases for Diabetic Patients Using Bacterial and Kombucha Tea Waste
In this study, the authors investigate the suitability of using bacterial cellulose as a scaffold for cell transplants. Interestingly, this cellulose is a can be found in the discard from a symbiotic culture of bacteria and yeast (SCOBY) used to make kombucha.
Read More...The Development of a Superhydrophobic Surface Using Electrolytic Deposition & Polymer Chains Precipitation
In this study, the authors were interested in developing a hydrophobic surface that will extend the lifespan of metals by reducing water exposure and other damage. The used a zinc coating on steel to pursue this effort.
Read More...Investigation of Everyday Locations for Antibiotic-Resistant Bacteria in Cambridge, Massachusetts
In this study, the authors investigate whether antibiotic-resistant bacteria can be found in everyday locations. To do this, they collected samples from multiple high-trafficked areas in Cambridge, MA and grew them in the presence and absence of antibiotics. Interestingly, they grew bacterial colonies from many locations' samples, but not all could grow in the presence of ampicillin. These findings are intriguing and relevant given the rising concern about antibiotic-resistant bacteria.
Read More...Phytochemical analysis of Annona Reticulata extract and an in-vitro study on its anti-proliferative effects
In this study, the authors investigate the anti-cancer effects of Annona Reticulata (Ramphal or custard apple) by testing whether its extract could inhibit HeLa cell viability.
Read More...The Effect of Common Cations on DNA Degradation
Heating of DNA-containing solutions is a part of many experiment protocols, but it can also cause damage and degradation of the DNA molecules, potentially leading to error in the experimental results. The authors of this paper investigate whether the presence of certain cations during heating can stabilize the DNA polymer and aid the preservation of the molecule.
Read More...Depression detection in social media text: leveraging machine learning for effective screening
Depression affects millions globally, yet identifying symptoms remains challenging. This study explored detecting depression-related patterns in social media texts using natural language processing and machine learning algorithms, including decision trees and random forests. Our findings suggest that analyzing online text activity can serve as a viable method for screening mental disorders, potentially improving diagnosis accuracy by incorporating both physical and psychological indicators.
Read More...Identifying 5-hydroxymethylcytosine as a potential cancer biomarker using FFPE DNA samples
This study used an improved CMS-seq method to profile 5hmC in ormalin-fixed and paraffin-embedded (FFPE) samples from HNC tumors and adjacent normal tissues, identifying three genes (PRKD2, HADHA, and AIPL1) with promising potential as biomarkers for Head and neck cancer (HNC) diagnosis.
Read More...