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Authors examine the impact of environmental noise on cognitive processes in teenagers, focusing on five different noise conditions: two types of noise (aircraft and construction) at two different decibel levels (30 dBA and 60 dBA) and a quiet condition.

The authors investigated prophages present in Streptococcus bacteria that may increase their survival in different environments.

This unique research study evaluated the potential use of the flatworm, brown planaria (Dugesia tigrine), as an alternative model for teratogenicity testing. In this study, we exposed amputated planaria to varying concentrations of a known teratogen, vitamin A (retinol), for approximately 2 weeks, and evaluated multiple parameters including the formation of blastema and eyes. The results from this study demonstrated that high concentrations of retinol caused defects in head and eye formation in regenerating planaria, with similarities to vitamin A related teratogenicity findings in mammals. Based on these results, regenerating brown planaria are a promising alternative model for teratogenicity testing, which can potentially be paradigm shifting as it can reduce cost, time, and pregnant animal use in research.

Here, the authors investigated alternative methods to irrigate plants based on the their identification that current irrigation systems waste a large amount of fresh water. They compared three different delivery methods for water: conventional sprinkler, underground cloth, and a perforated pipe embedded in the soil. They found the cloth method to save the most water, although plant growth was slightly less in comparison to plants watered with the sprinkler method or pipe method.

The authors explore how similar exoplanets are to Earth and whether they could be inhabited by humans and other living organisms.

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are allosteric inhibitors that bind to the HIV reverse transcriptase and prevent replication. Indolyl aryl sulfones (IAS) and IAS derivatives have been found to be highly effective against mutant strains of HIV-1 reverse transcriptase. Here, we analyzed molecules designed using aryl sulfone scaffolds paired to cyclic compounds as potential NNRTIs through the computational design and docking of 100 novel NNRTI candidates. Moreover, we explored the specific combinations of functional groups and aryl sulfones that resulted in the NNRTI candidates with the strongest binding affinity while testing all compounds for carcinogenicity. We hypothesized that the combination of an IAS scaffold and pyrimidine would produce the compounds with the best binding affinity. Our hypothesis was correct as the series of molecules with an IAS scaffold and pyrimidine exhibited the best average binding affinity. Additionally, this study found 32 molecules designed in this procedure with higher or equal binding affinities to the previously successful IAS derivative 5-bromo-3-[(3,5-dimethylphenyl)sulfonyl]indole-2-carboxyamide when docked to HIV-1 reverse transcriptase.

Recent declines in the brook trout population of the Lake Champlain Basin have made the genetic screening of this and other trout species of utmost importance. In this study, the authors collected and analyzed 21 DNA samples from Lake Champlain Basin trout populations and performed a phylogenetic analysis on these samples using the cytochrome b gene. The findings presented in this study may influence future habitat decisions in this region.

The authors assessed the degree of women participation in India's economy as a way to estimate woman's participation in India's economic growth.

This study used an improved CMS-seq method to profile 5hmC in ormalin-fixed and paraffin-embedded (FFPE) samples from HNC tumors and adjacent normal tissues, identifying three genes (PRKD2, HADHA, and AIPL1) with promising potential as biomarkers for Head and neck cancer (HNC) diagnosis.

The authors investigate whether air quality impacts solar production.