Browse Articles

The optical possibilities of gelatin

Parikh et al. | Mar 28, 2024

The optical possibilities of gelatin
Image credit: Lensabl

Here the authors investigated the optical possibilities of gelatin and acrylic in regards to potential implementations at soft contact lenses. They fabricated lenses of different shapes and evaluated the refraction of laser light finding that gelatin needed to be thickened or increased in curvature to account for its lower refractive index compared to plastics, or used in a mixture to strengthen the lens.

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The impact of genetic analysis on the early detection of colorectal cancer

Agrawal et al. | Aug 24, 2023

The impact of genetic analysis on the early detection of colorectal cancer

Although the 5-year survival rate for colorectal cancer is below 10%, it increases to greater than 90% if it is diagnosed early. We hypothesized from our research that analyzing non-synonymous single nucleotide variants (SNVs) in a patient's exome sequence would be an indicator for high genetic risk of developing colorectal cancer.

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Maximizing anaerobic biogas production using temperature variance

Verma et al. | Aug 03, 2023

Maximizing anaerobic biogas production using temperature variance

We conducted this research as our start-up's research that addresses the problem of biogas production in cow-dense regions like India. We hypothesized that the thermophilic temperature (45-60oC) would increase biogas production. The production process is much faster and more abundant at temperatures around 55-60oC.

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Transfer learning and data augmentation in osteosarcoma cancer detection

Chu et al. | Jun 03, 2023

Transfer learning and data augmentation in osteosarcoma cancer detection
Image credit: Chu and Khan 2023

Osteosarcoma is a type of bone cancer that affects young adults and children. Early diagnosis of osteosarcoma is crucial to successful treatment. The current methods of diagnosis, which include imaging tests and biopsy, are time consuming and prone to human error. Hence, we used deep learning to extract patterns and detect osteosarcoma from histological images. We hypothesized that the combination of two different technologies (transfer learning and data augmentation) would improve the efficacy of osteosarcoma detection in histological images. The dataset used for the study consisted of histological images for osteosarcoma and was quite imbalanced as it contained very few images with tumors. Since transfer learning uses existing knowledge for the purpose of classification and detection, we hypothesized it would be proficient on such an imbalanced dataset. To further improve our learning, we used data augmentation to include variations in the dataset. We further evaluated the efficacy of different convolutional neural network models on this task. We obtained an accuracy of 91.18% using the transfer learning model MobileNetV2 as the base model with various geometric transformations, outperforming the state-of-the-art convolutional neural network based approach.

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Modeling and optimization of epidemiological control policies through reinforcement learning

Rao et al. | May 23, 2023

Modeling and optimization of epidemiological control policies through reinforcement learning

Pandemics involve the high transmission of a disease that impacts global and local health and economic patterns. Epidemiological models help propose pandemic control strategies based on non-pharmaceutical interventions such as social distancing, curfews, and lockdowns, reducing the economic impact of these restrictions. In this research, we utilized an epidemiological Susceptible, Exposed, Infected, Recovered, Deceased (SEIRD) model – a compartmental model for virtually simulating a pandemic day by day.

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Error mitigation of quantum teleportation on IBM quantum computers

Chen et al. | May 15, 2023

Error mitigation of quantum teleportation on IBM quantum computers

Quantum computers can perform computational tasks beyond the capability of classical computers, such as simulating quantum systems in materials science and chemistry. Quantum teleportation is the transfer of quantum information across distances, relying on entangled states generated by quantum computing. We sought to mitigate the error of quantum teleportation which was simulated on IBM cloud quantum computers.

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Time-Efficient and Low-Cost Neural Network to detect plant disease on leaves and reduce food loss and waste

Singh et al. | Apr 24, 2023

Time-Efficient and Low-Cost Neural Network to detect plant disease on leaves and reduce food loss and waste

About 25% of the food grown never reaches consumers due to spoilage, and 11.5 billion pounds of produce from gardens are wasted every year. Current solutions involve farmers manually looking for and treating diseased crops. These methods of tending crops are neither time-efficient nor feasible. I used a convolutional neural network to identify signs of plant disease on leaves for garden owners and farmers.

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Can the nucleotide content of a DNA sequence predict the sequence accessibility?

Balachandran et al. | Mar 10, 2023

Can the nucleotide content of a DNA sequence predict the sequence accessibility?
Image credit: Warren Umoh

Sequence accessibility is an important factor affecting gene expression. Sequence accessibility or openness impacts the likelihood that a gene is transcribed and translated into a protein and performs functions and manifests traits. There are many potential factors that affect the accessibility of a gene. In this study, our hypothesis was that the content of nucleotides in a genetic sequence predicts its accessibility. Using a machine learning linear regression model, we studied the relationship between nucleotide content and accessibility.

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Tomato disease identification with shallow convolutional neural networks

Trinh et al. | Mar 03, 2023

Tomato disease identification with shallow convolutional neural networks

Plant diseases can cause up to 50% crop yield loss for the popular tomato plant. A mobile device-based method to identify diseases from photos of symptomatic leaves via computer vision can be more effective due to its convenience and accessibility. To enable a practical mobile solution, a “shallow” convolutional neural networks (CNNs) with few layers, and thus low computational requirement but with high accuracy similar to the deep CNNs is needed. In this work, we explored if such a model was possible.

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