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Varying Growth Hormone Levels in Chondrocytes Increases Proliferation Rate and Collagen Production by a Direct Pathway

Bennett et al. | Sep 03, 2019

Varying Growth Hormone Levels in Chondrocytes Increases Proliferation Rate and Collagen Production by a Direct Pathway

Bennett and Joykutty test whether growth hormone directly or indirectly affected the rate at which cartilage renewed itself. Growth hormone could exert a direct effect on cartilage or chondrocytes by modifying the expression of different genes, whereas an indirect effect would come from growth hormone stimulating insulin-like growth factor. The results from this research support the hypothesis that growth hormone increases proliferation rate using the direct pathway. This research can be used in the medical sciences for people who suffer from joint damage and other cartilage-related diseases, since the results demonstrated conditions that lead to increased proliferation of chondrocytes. These combined results could be applied in a clinical setting with the goal of allowing patient cartilage to renew itself at a faster pace, therefore keeping those patients out of pain from these chondrocyte-related diseases.

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Antibacterial activity by Dombeya wallichii plant extracts obtained by ultrasound-assisted extraction

Herur et al. | Nov 13, 2023

Antibacterial activity by <em>Dombeya wallichii</em> plant extracts obtained by ultrasound-assisted extraction

Medicinal plants could be a good source of medication to combat antibiotic resistance. Dombeya wallichii, which is commonly called Pink Ball Tree in the family Sterculiaceae, has been documented to have medicinal potential. We observed the highest antibacterial activity in the stem extracts, followed by leaf and bark extracts. The extracts were more effective against tested Gram-positive bacteria when compared with Gram-negative strains.

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The Effects of Barley Straw (Hordeum vulgare) Extract and Barley Straw Pellets on Algal Growth and Water Quality

McHargue et al. | Oct 06, 2020

The Effects of Barley Straw (Hordeum vulgare) Extract and Barley Straw Pellets on Algal Growth and Water Quality

Algal overgrowth often threatens to clog irrigation pipes and drinking water lines when left unchecked, as well as releasing possible toxins that threaten plant and human health. It is thus important to find natural, non-harmful agents that can decrease algal growth without threatening the health of plants and humans. In this paper, the authors test the efficacy of barely extract in either liquid or pellet form in decreasing algal growth. While their results were inconclusive, the experimental set-up allows them to investigate a wider range of agents as anti-algal treatments that could potentially be adopted on a wider scale.

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Combating Insulin Resistance Using Medicinal Plants as a Supplementary Therapy to Metformin in 3T3-L1 Adipocytes: Improving Early Intervention-Based Diabetes Treatment

Jayram et al. | Apr 08, 2019

Combating Insulin Resistance Using Medicinal Plants as a Supplementary Therapy to Metformin in 3T3-L1 Adipocytes: Improving Early Intervention-Based Diabetes Treatment

A primary cause of diabetes is insulin resistance, which is caused by disruption of insulin signal transduction. The objective of this study was to maximize insulin sensitivity by creating a more effective, early intervention-based treatment to avert severe T2D. This treatment combined metformin, “the insulin sensitizer”, and medicinal plants, curcumin, fenugreek, and nettle.

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Alloferon improves the growth performance and developmental time of mealworms (Tenebrio molitor)

Shon et al. | Oct 20, 2023

Alloferon improves the growth performance and developmental time of mealworms <em>(Tenebrio molitor)</em>

Mealworms (Tenebrio molitor) are important food sources for reptiles, birds, and other organisms, as well as for humans. However, the slow growth and low survival rate of mealworms cause problems for mass production. Since alloferon, a synthetic peptide, showed long-term immunological effects on mealworms, we hypothesized that alloferon would function as a growth promoter to maximize mealworm production. We discovered that the overall weight of the alloferon-containing gelatin diet group was 39.5-90% heavier, and the development time of the experimental group was shortened up to 20.6-39.6% than the control group.

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The effect of floating plant on water purification: Comparison of the water purification capability of Water Hyacinth, Duckweed, and Azolla

Park et al. | Nov 21, 2020

The effect of floating plant on water purification: Comparison of the water purification capability of Water Hyacinth, Duckweed, and Azolla

Clean water is a necessity for every household, yet water pollution is a serious problem in many parts of the world and plays a major role in compromising water security in the 21st century. In this paper, the authors address the utility of several plants as natural water purifiers. They estimate the effectiveness of duckweed, hyacinth, and azolla in improving the quality of water from the Mithi river in India by measuring several metrics. They conclude that all three plants are effective in improving water quality, suggesting that these plants as eco-friendly options for water treatment.

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Analysis of biofertilization impacts on Pisum sativum

Holden et al. | May 18, 2023

Analysis of biofertilization impacts on <i>Pisum sativum</i>
Image credit: David Boozer

This study explored the various effects of three different produce-based biofertilizers on pea plant growth, using red apple, pear, strawberry, and control treatments. It was hypothesized that the application of fruit biomatter would increase the growth of pea plants, with the application of strawberry biomatter having the most significant effect due to strawberries containing a higher nutrient content compared to pears and apples. Analysis confirmed the hypothesis. The application of strawberry biomatter could prove to be an effective way to increase plant growth in commercial agriculture.

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Can the Growth Mindset Encourage Girls to Pursue “Male” Careers?

Lateef et al. | Oct 03, 2021

Can the Growth Mindset Encourage Girls to Pursue “Male” Careers?

Despite major advances in gender equality, men still far outnumber women in science, technology, engineering and math (STEM) professions. The purpose of this project was to determine whether mindset could affect a student’s future career choices and whether this effect differed based on gender. When looking within the gender groups, 86% of females who had a growth mindset were likely to consider a “male” career, whereas only 16% of females with fixed mindset would likely to consider a “male” career. Especially for girls, cultivating a growth mindset may be a great strategy to address the problem of fewer girls picking STEM careers.

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Effect of Different Growth Media on Algae’s Ability for Carbon Dioxide Biofixation

Chaudhuri et al. | Oct 12, 2020

Effect of Different Growth Media on Algae’s Ability for Carbon Dioxide Biofixation

In this study, the authors investigate the effects of different algal growth media on algae's ability to perform carbon dioxide biofixation, or utilize carbon dioxide by fixing it into fatty acids within the cells. More specifically, carbon dioxide biofixation of Chlorella vulgaris was cultured in one of four media options and carbon dioxide was measured and compared to controls. The study results demonstrated that the use of media can enhance algae's capacity for biofixation and this has important implications for developing methods to reduce carbon dioxide in the environment.

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Developing novel plant waste-based hydrogels for skin regeneration and infection detection in diabetic wounds

Mathew et al. | Aug 10, 2023

Developing novel plant waste-based hydrogels for skin regeneration and infection detection in diabetic wounds

The purpose of this investigation is to develop a hydrogel to aid skin regeneration by creating an extracellular matrix for fibroblast growth with antibacterial and infection-detection properties. Authors developed two natural hydrogels based on pectin and potato peels and characterized the gels for fibroblast compatibility through rheology, scanning electron microscopy, swelling, degradation, and cell cytotoxicity assays. Overall, this experiment fabricated various hydrogels capable of acting as skin substitutes and counteracting infections to facilitate wound healing. Following further testing and validation, these hydrogels could help alleviate the 13-billion-dollar financial burden of foot ulcer treatment.

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