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A Novel Method for Auto-Suturing in Laparoscopic Robotic-Assisted Coronary Artery Bypass Graft (CABG) Anastomosis

Levy et al. | Jun 21, 2018

A Novel Method for Auto-Suturing in Laparoscopic Robotic-Assisted Coronary Artery Bypass Graft (CABG) Anastomosis

Levy & Levy tackle the optimization of the coronary artery bypass graft, a life-saving surgical technique that treats artery blockage due to coronary heart disease. The authors develop a novel auto-suturing method that saves time, allows for an increased number of sutures, and improves graft quality over hand suturing. The authors also show that increasing the number of sutures from four to five with their new method significantly improves graft quality. These promising findings may help improve outcomes for patients undergoing surgery to treat coronary heart disease.

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Molecular Alterations in a High-Fat Mouse Model Before the Onset of Diet–Induced Nonalcoholic Fatty Liver Disease

Lee et al. | Sep 20, 2016

Molecular Alterations in a High-Fat Mouse Model Before the Onset of Diet–Induced Nonalcoholic Fatty Liver Disease

Nonalcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver diseases worldwide, but there are few studied warning signs for early detection of the disease. Here, researchers study alterations that occur in a mouse model of NAFLD, which indicate the onset of NAFLD sooner. Earlier detection of diseases can lead to better prevention and treatment.

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Factors Influencing Muon Flux and Lifetime: An Experimental Analysis Using Cosmic Ray Detectors

Samson et al. | May 18, 2020

Factors Influencing Muon Flux and Lifetime: An Experimental Analysis Using Cosmic Ray Detectors

Muons, one of the fundamental elementary particles, originate from the collision of cosmic rays with atmospheric particles and are also generated in particle accelerator collisions. In this study, Samson et al analyze the factors that influence muon flux and lifetime using Cosmic Ray Muon Detectors (CRMDs). Overall, the study suggests that water can be used to decrease muon flux and that scintillator orientation is a potential determinant of the volume of data collected in muon decay studies.

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Mechanistic deconvolution of autoreduction in tetrazolium-based cell viability assays

Tran et al. | Jul 12, 2024

Mechanistic deconvolution of autoreduction in tetrazolium-based cell viability assays

Optical reporters like tetrazolium dyes, exemplified by 5-diphenyl tetrazolium bromide (MTT), are effective tools for quantifying cellular responses under experimental conditions. These dyes assess cell viability by producing brightly-colored formazan dyes when reduced inside active cells. However, certain small molecules, including reducing agents like ascorbic acid, cysteine, and glutathione (GSH), can interfere with MTT assays, potentially compromising accuracy.

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Obscurity of eyebrows influences recognition of human emotion and impacts older adolescents

Zhang et al. | Jan 20, 2025

Obscurity of eyebrows influences recognition of human emotion and impacts older adolescents
Image credit: Ernesto Norman

Here, seeking to better understand how facial features provide important visual cues to help convey emotions, the authors evaluated the accuracy and reaction time of participants in regards to experimental photographs where a person's eyebrows were obscured and ones where they were not. Their findings revealed that removing eyebrows resulted in a significant decrease in a participant's ability to recognize anger, with adolescents most likely to misidentify emotions.

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