A common form of Acne is caused by a species of bacterium called Cutibacterium acnes. By using a predictive algorithm and structural analysis, the authors identified 5 small molecules with high affinity to growth factors in Catibacterium acnes. This has potential implications for supplemental skincare products.
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In vitro Comparison of Anticancer and Immunomodulatory Activities of Resveratrol and its Oligomers

Resveratrol is a type of stillbenoid, a phenolic compound produced in plants, that is known for its anti-inflammatory and anticancer effects. Many oligomers of resveratrol have recently been isolated their bioactivities remain unknown. Here, authors compared the bioactivities of resveratrol with natural dimers (ε-viniferin and gnetin H) and trimers (suffruticosol B and C). Results provide preliminary evidence that resveratrol oligomers could be potential preventive or therapeutic agents for cancers and other immune-related diseases
Read More...Investigating intertidal sediment sorting and median particle diameter variation on an eroding beach face

The authors looked at beach nourishment (a way to combat erosion on coasts) and resulting grain size distribution. Their work is important to understand the dynamics of erosion and it's relation to wave action and the implications this has for efforts to mitigate coastal erosion.
Read More...Mechanism and cytotoxicity of A1874 proteolysis targeting chimera on CT26 colon carcinoma cell line

This study investigates the effects of the PROTAC compound A1874 on CT26 colon carcinoma cells, focusing on its ability to degrade the protein BRD4 and reduce cell viability. While A1874 had previously shown effectiveness in other colon cancer cell lines, its impact on CT26 cells was unknown.
Read More...Country-level relationship of OTC medicine consumption and frequency of GP consultation

The discussion surrounding self-medication with non-prescription medicines has gained significance in healthcare and public health, particularly given the global increase in consumption of non-prescription drugs. This study aimed to examine the association between the frequency of general practitioner (GP) consultations and the proportion of economic resources spent on OTC medicine.
Read More...Convolutional neural network-based analysis of pediatric chest X-ray images for pneumonia detection

The authors test various machine learning models to improve the accuracy and efficiency of pneumonia diagnosis from X-ray images.
Read More...Stress and depression among individuals with low socioeconomic status during economic inflation

The authors use the Census Household Pulse Survey issued by the US Census Bureau to examine the prevalence of stress and depression among people across socioeconomic statuses.
Read More...Percentages are a better format for conveying medical risk than frequencies

It can be challenging for the general public to understand data on medical risk. Weseley-Jones and Mordechai tackle this issue by conducting a survey to assess people's skill and comfort with understanding medical risk information in percentage and frequency formats.
Read More...Impacts of the gut microbiota on arginine synthesis

In this article the authors looked at arginine synthesis across different bacteria commonly found in different regional diets. They found that B. megaterium and C. sporogenes both caused a higher pH to occur on their agar plates compared to other bacteria tested indicating a greater amount of arginine synthesis.
Read More...Studying the effects of different anesthetics on quasi-periodic patterns in rat fMRI

The authors looked at the effects of commonly used anesthetics in rodents on brain activity (specifically quasi-periodic patterns). Understanding effects on brain activity is important for researchers to understand when choosing rodent models for disease.
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