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The analysis of the viral transmission and structural interactions between the HIV-1 envelope glycoprotein and the lymphocyte receptor integrin α4β7

Ganesh et al. | Apr 28, 2021

The analysis of the viral transmission and structural interactions between the HIV-1 envelope glycoprotein and the lymphocyte receptor integrin α4β7

The Human Immunodeficiency Virus (HIV) infects approximately 40 million people globally, and one million people die every year from Acquired Immune Deficiency Syndrome (AIDS)-related illnesses. This study examined the interactions between the HIV-1 envelope glycoprotein gp120 and the human lymphocyte receptor integrin α4β7, the putative first long-range receptor for the envelope glycoprotein of the virus in mucosal tissues. Presented data support the claim that the V1 loop is involved in the binding between α4β7 and the HIV-1 envelope glycoprotein through molecular dockings.

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The Impact of the COVID-19 Pandemic on Mental Health of Teens

Qureshi et al. | Nov 19, 2020

The Impact of the COVID-19 Pandemic on Mental Health of Teens

In this study, the authors investigate whether the COVID-19 pandemic is affecting the mental health of teens. Using data from a study done in Islamabad, Pakistan, the authors find that many teens between the ages of 13 and 19 show signs of mental illness. This study reports important data regarding the mental health of youth and points toward an increased need to address this topic during the pandemic.

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Testing HCN1 channel dysregulation in the prefrontal cortex using a novel piezoelectric silk neuromodulator

Mathew et al. | May 05, 2021

Testing HCN1 channel dysregulation in the prefrontal cortex using a novel piezoelectric silk neuromodulator

Although no comprehensive characterization of schizophrenia exists, there is a general consensus that patients have electrical dysfunction in the prefrontal cortex. The authors designed a novel piezoelectric silk-based implant and optimized electrical output through the addition of conductive materials zinc oxide (ZnO) and aluminum nitride (AlN). With further research and compatibility studies, this implant could rectify electrical misfiring in the infralimbic prefrontal cortex.

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The effects of age on quality of mental health during the COVID-19 pandemic

Bui et al. | Jul 15, 2024

The effects of age on quality of mental health during the COVID-19 pandemic

The impact of age on mental health is a crucial yet understudied aspect of public health. While mental health is gaining recognition as a vital component of overall well-being, its correlation with age remains largely unexplored. In Canada, where the median age has risen significantly over the past half-century, understanding this relationship becomes increasingly pertinent. Researchers hypothesized that older adults would exhibit lower rates of mental health disorders and report better perceived mental health due to increased emotional stability and maturity.

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Evaluating cinnamaldehyde as an antibacterial agent in a produce wash for leafy greens

Drennan et al. | Oct 28, 2021

Evaluating cinnamaldehyde as an antibacterial agent in a produce wash for leafy greens

Recognizing a growing demand for organic produce, the authors sought to investigate plant-based antibiotic solutions to meet growing consumer demand for safe produce and also meet microbial standards of the USDA. The authors investigated the use of cinnamaldehyde as an antibacterial again E. coli, finding that lettuce treated with cinnamaldehyde displayed significantly lower colony-forming units of E. coli when compared to lettuce treated with chlorine bleach.

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