The authors looked at the ability of different deep learning models to predict the presence of lung cancer from chest CT scans. They found that a pre-trained CNN model performed better than an autoencoder model.
Read More...How artificial intelligence deep learning models can be used to accurately determine lung cancers
The authors looked at the ability of different deep learning models to predict the presence of lung cancer from chest CT scans. They found that a pre-trained CNN model performed better than an autoencoder model.
Read More...Temporal characterization of electroencephalogram slowing activity types
The authors use machine learning to analyze electroencephalogram data and identify slowing patterns that can indicate undetected disorders like epilepsy or dementia
Read More...Estimation of Reproduction Number of Influenza in Greece using SIR Model
In this study, we developed an algorithm to estimate the contact rate and the average infectious period of influenza using a Susceptible, Infected, and Recovered (SIR) epidemic model. The parameters in this model were estimated using data on infected Greek individuals collected from the National Public Health Organization. Our model labeled influenza as an epidemic with a basic reproduction value greater than one.
Read More...Relationship between p62 and learning behavior in male and female mice deficient in hippocampal folliculin
Here the authors hypothesized that reducing folliculin (FLCN) might affect p62 protein levels in the dorsal hippocampus of mice, given their potential functional connection and p62's role in neurodegenerative diseases. Their study, using western blots and a two-way ANOVA on young wild-type mice, found that p62 levels correlated with FLCN expression, but ultimately concluded there's no evidence of a functional connection between FLCN and p62 in this specific model.
Read More...Reduced psoriasis skin irritation symptoms through the effects of Chinese herbal medicines on planarians
The authors looked at whether traditional Chinese medicine remedies that target the lungs and liver would reduce inflammation in a planaria model. They found that the two active compounds they tested were able to decrease induced inflammation by 97-98%.
Read More...Association between nonpharmacological interventions and dementia: A retrospective cohort study
Here, the authors investigated the role of nonpharmacological interventions in preventing or delaying cognitive impairment in individuals with and without dementia. By using a retrospective case-control study of 22 participants across two senior centers in San Diego, they found no significant differences in self-reported activities. However, they found that their results reflected activity rather than the activity itself, suggesting the need for an alternative type of study.
Read More...Identification of a core set of model agnostic mRNA associated with nonalcoholic steatohepatitis (NASH)
In this study, the authors analyze gene expression datasets to determine if there is a core set of genes dysregulated during nonalcoholic steatohepatitis.
Read More...Anticancer, anti-inflammatory, and apoptotic activities of MAT20, a poly-herbal formulation.
Kashyap Jha et al. look at the formulation of MAT20, a crude extract of the moringa, amla, and tulsi leaves, as a potential complementary and alternative medicine. Using HeLa cells, they find MAT20 up-regulates expression of inflammation and cell cytotoxicity markers. Their data is important for understanding the anti-cancer and anti-inflammatory properties of MAT20.
Read More...DNA-SEnet: A convolutional neural network for classifying DNA-asthma associations
In this study, the authors developed a model named DNA Sequence Embedding Network (DNA-SEnet) to classify DNA-asthma associations using their genomic patterns.
Read More...Effect of the Herbal Formulation HF1 on the Expression of PD-L1 in PC3 cells
In this study, Imani et al. investigate whether a new proprietary herbal formulation, HF1, can inhibit expression of immune suppressor protein PD-L1. PD-L1 is a transmembrane protein that can be expressed by cancer cells to assist in their ability to avoid attacks from the immune system. Work from this study demonstrates that HF1 treatment can reduce expression of PD-L1 in cultured cancer cells, implicating HF1 as a potential new cancer therapy.
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