Here, recognizing the difficulty associated with tracking the progression of dementia, the authors used machine learning models to predict between the presence of cognitive normalcy, mild cognitive impairment, and Alzheimer's Disease, based on blood DNA methylation levels, sex, and age. With four machine learning models and two dataset dimensionality reduction methods they achieved an accuracy of 53.33%.

Childhood abuse has severe and lasting effects throughout an individual's life, and may even have long-term biological effects on individuals who suffer it. To learn more about the effects of abuse in childhood, Li and Yearwood analyze gene expression data to look for genes differentially expressed genes in individuals with a history of childhood abuse.