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Risk assessment modeling for childhood stunting using automated machine learning and demographic analysis

Sirohi et al. | Sep 25, 2022

Risk assessment modeling for childhood stunting using automated machine learning and demographic analysis

Over the last few decades, childhood stunting has persisted as a major global challenge. This study hypothesized that TPTO (Tree-based Pipeline Optimization Tool), an AutoML (automated machine learning) tool, would outperform all pre-existing machine learning models and reveal the positive impact of economic prosperity, strong familial traits, and resource attainability on reducing stunting risk. Feature correlation plots revealed that maternal height, wealth indicators, and parental education were universally important features for determining stunting outcomes approximately two years after birth. These results help inform future research by highlighting how demographic, familial, and socio-economic conditions influence stunting and providing medical professionals with a deployable risk assessment tool for predicting childhood stunting.

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Employee resignation study in Fairfax County

Zhang et al. | Mar 03, 2023

Employee resignation study in Fairfax County

In this study, the authors address potential reasons why employees may voluntarily resign. This is in response to the currently observed economic trend The Great Resignation. Through analysis of federal and local government data along with survey results from Fairfax County, they concluded that adding additional benefits will help companies retain talented empolyees.

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The Long-Term Effect of CBD Crystals and CBD Oil on Depressive-Associated Rat Behaviors

Yang et al. | Dec 18, 2020

The Long-Term Effect of CBD Crystals and CBD Oil on Depressive-Associated Rat Behaviors

Cannabidiol (CBD) is a chemical extracted from cannabis and shown by some studies to alleviate the symptoms of many mental disorders, especially major depressive disorder. The authors hypothesized that chronic treatments with purified CBD through oral administration would relieve depression-associated behaviors in normal healthy rats under adverse conditions. A statistical analysis of the experimental data suggested that long-term consumption of CBD could elicit depression associated symptoms in normal rats without depression. The results imply that people should consume CBD-containing products with extreme caution and highlight the need to carefully monitor the use of CBD in health care products.

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Refinement of Single Nucleotide Polymorphisms of Atopic Dermatitis related Filaggrin through R packages

Naravane et al. | Oct 12, 2022

Refinement of Single Nucleotide Polymorphisms of Atopic Dermatitis related Filaggrin through R packages

In the United States, there are currently 17.8 million affected by atopic dermatitis (AD), commonly known as eczema. It is characterized by itching and skin inflammation. AD patients are at higher risk for infections, depression, cancer, and suicide. Genetics, environment, and stress are some of the causes of the disease. With the rise of personalized medicine and the acceptance of gene-editing technologies, AD-related variations need to be identified for treatment. Genome-wide association studies (GWAS) have associated the Filaggrin (FLG) gene with AD but have not identified specific problematic single nucleotide polymorphisms (SNPs). This research aimed to refine known SNPs of FLG for gene editing technologies to establish a causal link between specific SNPs and the diseases and to target the polymorphisms. The research utilized R and its Bioconductor packages to refine data from the National Center for Biotechnology Information's (NCBI's) Variation Viewer. The algorithm filtered the dataset by coding regions and conserved domains. The algorithm also removed synonymous variations and treated non-synonymous, frameshift, and nonsense separately. The non-synonymous variations were refined and ordered by the BLOSUM62 substitution matrix. Overall, the analysis removed 96.65% of data, which was redundant or not the focus of the research and ordered the remaining relevant data by impact. The code for the project can also be repurposed as a tool for other diseases. The research can help solve GWAS's imprecise identification challenge. This research is the first step in providing the refined databases required for gene-editing treatment.

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Gradient boosting with temporal feature extraction for modeling keystroke log data

Barretto et al. | Oct 04, 2024

Gradient boosting with temporal feature extraction for modeling keystroke log data
Image credit: Barretto and Barretto 2024.

Although there has been great progress in the field of Natural language processing (NLP) over the last few years, particularly with the development of attention-based models, less research has contributed towards modeling keystroke log data. State of the art methods handle textual data directly and while this has produced excellent results, the time complexity and resource usage are quite high for such methods. Additionally, these methods fail to incorporate the actual writing process when assessing text and instead solely focus on the content. Therefore, we proposed a framework for modeling textual data using keystroke-based features. Such methods pay attention to how a document or response was written, rather than the final text that was produced. These features are vastly different from the kind of features extracted from raw text but reveal information that is otherwise hidden. We hypothesized that pairing efficient machine learning techniques with keystroke log information should produce results comparable to transformer techniques, models which pay more or less attention to the different components of a text sequence in a far quicker time. Transformer-based methods dominate the field of NLP currently due to the strong understanding they display of natural language. We showed that models trained on keystroke log data are capable of effectively evaluating the quality of writing and do it in a significantly shorter amount of time compared to traditional methods. This is significant as it provides a necessary fast and cheap alternative to increasingly larger and slower LLMs.

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Color photometry and light curve modeling of apparent transient 2023jri

Favretto et al. | Aug 13, 2024

Color photometry and light curve modeling of apparent transient 2023jri

Observing transients like supernovae, which have short-lived brightness variations, helps astronomers understand cosmic phenomena. This study analyzed transient 2023jri, hypothesizing it was a Type IIb supernova. By collecting and analyzing data over four weeks, including light and color curves, they confirmed its classification and provided additional insights into this less-studied supernova type.

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