The major drawback of chemotherapy regimens for treating cancer is that the cancerous cells acquire drug resistance and become impervious to further dose escalation. Keeping in mind the studied success of herbal formulations with regard to alternative treatments for cancer, we hypothesized that the use of a chemotherapeutic drug and proprietary herbal formulation, HF1, would combat this phenomenon when administered with common chemotherapeutic drug 5FU. Results demonstrated a cooperative effect between HF1 and 5FU on the drug resistant cell line, implying that administration of HF1 with 5FU results in cell death as measured by MTT assay.
In this study, the authors characterized the trends of cigarette use amongst people who do and don't use electronic nicotine delivery systems (or ENDS). This was done to help determine if the use of ENDS is aiding in helping smokers quit, as the data on this has been controversial. They found that use of ENDS among people either with or without previous cigarette usage were more likely to continue using cigarettes in the future. This is important information contributing to our understanding of ways to effectively (and not effectively) reduce cigarette use.
Antibiotics are used to treat dangerous diseases. Over time, however, bacteria are becoming resistant to antibiotics - which poses a threat to humans and animals alike. In this paper, the authors examine how E. coli gains resistance to the antibiotic amoxicillin.
Overwatering and underwatering grass are widespread issues with environmental and financial consequences. This study developed an accessible method to assess grass water use efficiency (WUE) combining smartphone imaging with open access color unmixing analysis. The method can be applied in automated irrigation systems or apps, providing grass WUE assessment for regular consumer use.
Honey possesses distinctive antimicrobial properties; however, it is unknown which compounds in honey are responsible for these properties. In this research study, Abdel-Azim et al. examine the role of osmotic stress in honey and the antibacterial efficacy of both Manuka and raw pasture honey.
Disruptions to the microbiome, specifically the imbalance in the two major phyla, the Firmicutes and the Bacteroidetes, have been linked to the development of obesity. This study explored whether or not Fage plain total 0% Greek yogurt, which contains live and active bacterial cultures belonging to the Firmicute phylum, could decrease the numbers of Bacteroides thetaiotaomicron, an organism found in the human gut that belongs to the Bacteroidetes phylum.
Clean drinking water is an essential component to maintaining public health. The authors of this study tested the bacterial load of water from three different disinfection and filtration systems in order to determine which system might be superior.
The authors looked at using machine learning to identify skills needed to apply for certain jobs, specifically looking at different techniques to parse apart the text. They found that Bidirectional Encoder Representation of Transforms (BERT) performed best.
The advent of quantum computing will pose a substantial threat to the security of classical cryptographic methods, which could become vulnerable to quantum-based attacks. In response to this impending challenge, the field of post-quantum cryptography has emerged, aiming to develop algorithms that can withstand the computational power of quantum computers. This study addressed the pressing concern of classical cryptographic methods becoming vulnerable to quantum-based attacks due to the rise of quantum computing. The emergence of post-quantum cryptography has led to the development of new resistant algorithms. Our research focused on four quantum-resistant algorithms endorsed by America’s National Institute of Standards and Technology (NIST) in 2022: CRYSTALS-Kyber, CRYSTALS-Dilithium, FALCON, and SPHINCS+. This study evaluated the security, performance, and comparative attributes of the four algorithms, considering factors such as key size, encryption/decryption speed, and complexity. Comparative analyses against each other and existing quantum-resistant algorithms provided insights into the strengths and weaknesses of each program. This research explored potential applications and future directions in the realm of quantum-resistant cryptography. Our findings concluded that the NIST algorithms were substantially more effective and efficient compared to classical cryptographic algorithms. Ultimately, this work underscored the need to adapt cryptographic techniques in the face of advancing quantum computing capabilities, offering valuable insights for researchers and practitioners in the field. Implementing NIST-endorsed quantum-resistant algorithms substantially reduced the vulnerability of cryptographic systems to quantum-based attacks compared to classical cryptographic methods.
.jpg)
