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Identification of potential therapeutic targets for multiple myeloma by gene expression analysis

Kochenderfer et al. | Apr 26, 2024

Identification of potential therapeutic targets for multiple myeloma by gene expression analysis
Image credit: The authors

A central challenge of cancer therapy is identifying treatments that will effectively target cancer cells while minimizing effects on healthy cells. To identify potential targets for treating a multiple myeloma, a frequently incurable cancer, Kochenderfer and Kochenderfer analyze RNA sequencing data from the Cancer Cell Line Encyclopedia to find genes with high expression in multiple myeloma cells and low expression in normal tissues

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Genetic underpinnings of the sex bias in autism spectrum disorder

Lee et al. | Mar 29, 2024

Genetic underpinnings of the sex bias in autism spectrum disorder
Image credit: Louis Reed

Here, seeking to identify a possible explanation for the more frequent diagnosis of autism spectrum disorder (ASD) in males than females, they sought to investigate a potential sex bias in the expression of ASD-associated genes. Based on their analysis, they identified 17 ASD-associated candidate genes that showed stronger collective sex-dependent expression.

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Analyzing the effects of multiple adhesives on elastic collisions and energy loss in a Newton’s Cradle

Isham et al. | Feb 02, 2024

Analyzing the effects of multiple adhesives on elastic collisions and energy loss in a Newton’s Cradle

The energy conservation in a system of objects in collision depends on the elasticity of the objects and environmental factors such as air resistance. One system that relies heavily on elasticity is the Newton’s Cradle. We aimed to determine the extent to which these adhesives serve to mitigate or worsen the chaotic movements and elastic collisions.

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Contribution of environmental factors to genetic variation in the Pacific white-sided dolphin

Talwar et al. | Jan 23, 2024

Contribution of environmental factors to genetic variation in the Pacific white-sided dolphin
Image credit: Flavio

Here the authors sought to understand the effects of different variables that may be tied to pollution and climate change on genetic variation of Pacific white-sided dolphins, a species that is currently threatened by water pollution. Based on environmental data collected alongside a genetic distance matrix, they found that ocean currents had the most significant impact on the genetic diversity of Pacific white-sided dolphins along the Japanese coast.

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Which fruit peel helps retain the most soil moisture?

Parashar et al. | Jan 09, 2024

Which fruit peel helps retain the most soil moisture?
Image credit: Anshu A

Here, the authors investigated the ability to use fruit peels to help soil retain moisture, a property that is essential to agriculture. Across a 96-hour observation period, orange, banana, and kiwi peel water emulsions were evaluated for their effects on soil moisture. They found that orange peels retained the most moisture, but banana and kiwi peels also offered improvements over their control sample.

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Therapy dogs effectively reduce stress in college preparatory students

Ikeda et al. | Nov 27, 2023

Therapy dogs effectively reduce stress in college preparatory students
Image credit: Ryan Stone

In this article the authors looked at the effect of spending time with a therapy dog before and after stressful events. They found that interacting with a therapy before a stressful event showed more significant reduction in signs of stress compared to interacting with a therapy dog after stressful events have already occurred.

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