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Cancer is often caused by improper function of a few proteins, and sometimes it takes only a few proteins to malfunction to cause drastic changes in cells. Here the authors look at the genes that were mutated in patients with a type of pancreatic cancer to identify proteins that are important in causing cancer. They also determined which proteins currently lack effective treatment, and suggest that certain proteins (named KRAS, CDKN2A, and RBBP8) are the most important candidates for developing drugs to treat pancreatic cancer.

The authors test the effect of petroleum-based and bio-based microplastics on the growth of two microalgae species.

The study explored converting Gracilaria seaweed waste—known for releasing toxic hydrogen sulfide when decomposed—into biochar as a sustainable solution for waste management and soil improvement.

Here the authors investigated the natural recovery of stress-induced dopamine-related gene deficits in C. elegans by measuring the expression of cat-2 (dopamine biosynthesis) and sod-2 (oxidative stress) following exposure to starvation or hydrocortisone. They found that the reversibility of sod-2 and the expression of cat-2 were highly dependent on the type and severity of the stressor, suggesting that the body's natural ability to recover from dopamine dysfunction has biological limitations.

The authors examined the effect of varying glucose concentrations on cut rose longevity.

The authors assess a genetic variant within a well-known interaction partner of huntingtin that has been linked to modifying the age of onset of Huntington's disease.

The authors design and test an easy-to-use and cost-effective mobile app-based alert system to help senior citizens rapidly communicate with caregivers in emergencies or when in need of assistance.

The authors looked at the impact of citrate and lactate on glioblastoma progression. Their results provide important insights for future immunotherapies aimed at treating glioblastoma.

Impact of carbon tax and dividend on financial security

Current osteosarcoma (OS) treatments rely on surgery and chemotherapy, but drug resistance remains a major challenge that lowers patient survival rates. Ferroptosis, a form of regulated cell death, has shown promise in cancer therapy but is not well understood in OS. This study explores the use of Ferroptosis in OS.