The authors looked at energy efficient ways to generate small nitrogenous compounds.
Read More...Nonthermal nitrogen fixation with air and water by using a low-pressure plasma
Exploring the possibilities for reactions between SiW and alkaline solutions to be renewable energy sources
The authors looked at hydrogen gas production and how reaction temperature, concentration and alkaline solution used impacted the overall reaction with silicon. They found that all alkaline solutions tested would be viable options for using silicon waste to produce hydrogen gas to be used a renewable energy source.
Read More...Characterizing the association between hippocampal reactive astrogliosis, anhedonia-like behaviors, and neurogenesis in a monkey model of stress and antidepressant treatment
This study examined the effects of stress and selective serotonin reuptake inhibitors (SSRIs) on a measure of astrocyte reactivity in nonhuman primate (NHP) models of stress. Results showed that chronic separation stress in NHPs leads to increased signs of astrogliosis in the NHP hippocampus. The findings were consistent with the hypotheses that hippocampal astrogliosis is an important mechanism in stress-induced cognitive and behavioral deficits.
Read More...Phospholipase A2 increases the sensitivity of doxorubicin induced cell death in 3D breast cancer cell models
Inefficient penetration of cancer drugs into the interior of the three-dimensional (3D) tumor tissue limits drugs' delivery. The authors hypothesized that the addition of phospholipase A2 (PLA2) would increase the permeability of the drug doxorubicin for efficient drug penetration. They found that 1 mM PLA2 had the highest permeability. Increased efficiency in drug delivery would allow lower concentrations of drugs to be used, minimizing damage to normal cells.
Read More...Modulation of Planaria Regeneration by Resolvin D1 and the Omega-3 Fatty Acid Precursor 17-Hydroxy Docosahexaenoic Acid
Omega-3 fatty acid derived lipid mediators have been implicated in resolving inflammation, and wound healing. Authors measured the impact of supplementation with lipid mediator Resolvin D1 and its precursor 17-HDHA on planaria regeneration. Planaria not only synthesize RvD1 from 17-DHA, but both RvD1 and 17-DHA enhanced regeneration.
Read More...The Effect of Ethanol Concentration on Beta-Cell Development in Zebrafish
Alcohol is known to cause various developmental diseases including Fetal Alcohol Syndrome. Here the authors investigate the effect of ethanol on the development of zebrafish beta cells, the part of the pancreas associated with Type 1 Diabetes. They find that exposure to ethanol does adversely affect beta-cell development, suggesting that alcohol ingestion during pregnancy may be linked to diabetes in newborns.
Read More...The effects of plasticizers on the mechanical properties and chemical composition of a gelatin biopolymer
Here, in an effort to identify alternatives to oil-based plastic, the authors sought to investigate the effects of plasticizers on the mechanical properties and chemical composition of gelatin bioplastic matrices. Through measurements of their tensile strength and elongation at break, along with FTIR spectroscopy, they identified 3% w/v polyethylene glycol film as having the best performance in their study..
Read More...In vitro Comparison of Anticancer and Immunomodulatory Activities of Resveratrol and its Oligomers
Resveratrol is a type of stillbenoid, a phenolic compound produced in plants, that is known for its anti-inflammatory and anticancer effects. Many oligomers of resveratrol have recently been isolated their bioactivities remain unknown. Here, authors compared the bioactivities of resveratrol with natural dimers (ε-viniferin and gnetin H) and trimers (suffruticosol B and C). Results provide preliminary evidence that resveratrol oligomers could be potential preventive or therapeutic agents for cancers and other immune-related diseases
Read More...The Effects of L-glutamate, L-glutamine, and L-aspartic Acid on the Amylase Production of E. coli Transformed With pAmylase
Human amylase is important to digestion and has broad applications for therapeutic use in patients with pancreatic insufficiency. The authors present a method to increase amylase production in E. coli by adding the amino acids L-glutamate and L-glutamine.
Read More...Survival analysis in cardiovascular epidemiology: nexus between heart disease and mortality
In 2021, over 20 million people died from cardiovascular diseases, highlighting the need for a deeper understanding of factors influencing heart failure outcomes. This study examined multiple variables affecting mortality after heart failure, using random forest models to identify time, serum creatinine, and ejection fraction as key predictors. These findings could contribute to personalized medicine, improving survival rates by tailoring treatment strategies for heart failure patients.
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