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Socio-economic and awareness correlates of physical activity of government school children in India

Nandivada et al. | Dec 11, 2022

Socio-economic and awareness correlates of physical activity of government school children in India

Here, based on the identified importance of physical activity in the development of young children, the authors investigated the effects of socioeconomic factors on the amount of physical activity of government-school children in India. They found significant differences between boys and girls, rural and urban, and children who were encouraged to exercise and those who were not. Overall, they suggest that their findings point to the important role of schools and communities in promoting healthy active lifestyles for developing children.

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Mask wearing and oxyhemoglobin saturation effects during exercise

Foss et al. | Jul 15, 2022

Mask wearing and oxyhemoglobin saturation effects during exercise

Wearing face masks has become a common occurrence in everyday life and during athletics due to the spread of diseases. This study tested if masks would affect blood percent saturation of hemoglobin (SpO2) during treadmill exercise. The data analysis showed that mask type, time, and the interaction of mask type and time were significant results, regardless of physical ability. These results may assist athletes in understanding the differences between training and competing with and without a mask.

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Testing the Effects of Resveratrol, Apigenin, and Glucosamine to Effectively Reduce Prostate Cancer Cell Proliferation, Migration Levels, and Increase Apoptosis

Yang et al. | Apr 16, 2020

Testing the Effects of Resveratrol, Apigenin, and Glucosamine to Effectively Reduce Prostate Cancer Cell Proliferation, Migration Levels, and Increase Apoptosis

The current five-year survival rate of metastasized prostate cancer is only 30% and occurs in every one in nine men. Researchers have shown that people with a type of dwarfism called Laron’s Syndrome are immune to cancer due to their low levels of insulin-like growth factor-1 (IGF-1). For this reason, experimentally modifying the level of IGF-1 could provide better insight into whether lowering the levels of IGF-1 in prostate cancer cell lines (e.g. PC-3) could be an effective treatment to reduce their rates of proliferation and migration and increase apoptosis. We selected three compounds, which researchers have shown decrease IGF-1 levels, to test and combine to determine which is the most promising.

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Investigation of Everyday Locations for Antibiotic-Resistant Bacteria in Cambridge, Massachusetts

Maggio et al. | Dec 12, 2019

Investigation of Everyday Locations for Antibiotic-Resistant Bacteria in Cambridge, Massachusetts

In this study, the authors investigate whether antibiotic-resistant bacteria can be found in everyday locations. To do this, they collected samples from multiple high-trafficked areas in Cambridge, MA and grew them in the presence and absence of antibiotics. Interestingly, they grew bacterial colonies from many locations' samples, but not all could grow in the presence of ampicillin. These findings are intriguing and relevant given the rising concern about antibiotic-resistant bacteria.

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Effect of the Herbal Formulation HF1 on the Expression of PD-L1 in PC3 cells

Imani et al. | Nov 15, 2019

Effect of the Herbal Formulation HF1 on the Expression of PD-L1 in PC3 cells

In this study, Imani et al. investigate whether a new proprietary herbal formulation, HF1, can inhibit expression of immune suppressor protein PD-L1. PD-L1 is a transmembrane protein that can be expressed by cancer cells to assist in their ability to avoid attacks from the immune system. Work from this study demonstrates that HF1 treatment can reduce expression of PD-L1 in cultured cancer cells, implicating HF1 as a potential new cancer therapy.

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Effect of Manuka Honey and Licorice Root Extract on the Growth of Porphyromonas gingivalis: An In Vitro Study

Chandran et al. | Apr 11, 2018

Effect of Manuka Honey and Licorice Root Extract on the Growth of Porphyromonas gingivalis: An In Vitro Study

Chronic bad breath, or halitosis, is a problem faced by nearly 50% of the general poluation, but existing treatments such as liquid mouthwash or sugar-free gum are imperfect and temporary solutions. In this study, the authors investigate potential alternative treatments using natural ingredients such as Manuka Honey and Licorice root extract. They found that Manuka honey is almost as effective as commercial mouthwashes in reducing the growth of P gingivalis (one of the main bacteria that causes bad breath), while Licorice root extract was largely ineffective. The authors' results suggest that Manuka honey is a promising candidate in the search for new and improved halitosis treatments.

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The Impact of Age on Post-Concussive Symptoms: A Comparative Study of Symptoms Related and Not Related to the Default Mode Network

Wurscher et al. | Mar 05, 2017

The Impact of Age on Post-Concussive Symptoms: A Comparative Study of Symptoms Related and Not Related to the Default Mode Network

The Default Mode Network (DMN) is a network of connected brain regions that are active when the brain is not focused on external tasks. Minor brain injuries, such as concussions, can affect this network and manifest symptoms. In this study, the authors examined correlations between DMN age and post-concussion symptoms in previously concussed individuals and healthy controls.

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Identification of a Free Radical Scavenger as an Additive for Lung Transplant Preservation Solution to Inhibit Coagulative Necrosis and Extend Organ Preservation

Ganesh et al. | Feb 12, 2015

Identification of a Free Radical Scavenger as an Additive for Lung Transplant Preservation Solution to Inhibit Coagulative Necrosis and Extend Organ Preservation

During transfer of organs from a donor to a patient, the organs deteriorate in part due to damage by free radicals. Application of antioxidant solutions could extend organ preservation times. The authors found that vitamin E and butylated hydroxytoluene seemed to be most effective in arresting cell damage of a bovine lung.

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pH-dependent drug interactions with acid reducing agents

Lin et al. | Nov 12, 2024

pH-dependent drug interactions with acid reducing agents
Image credit: The authors

Some cancer treatments lose efficacy when combined with treatments for excessive stomach acid, due to the changes in the stomach environment caused by the stomach acid treatments. Lin and Lin investigate information on oral cancer drugs to see what information is available on interactions of these drugs.

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