Deciphering correlation and causation in risk factors for heart disease with Mendelian randomization
Here, seeking to identify the risk of coronary artery disease (CAD), a major cause of cardiovascular disease, the authors used Mendelian randomization. With this method they identified several traits such as blood pressure readings, LDL cholesterol and BMI as significant risk factors. While other traits were not found to be significant risk factors.
Read More...Evaluation of the causality between testosterone, obesity, and diabetes
The study explored the role of testosterone beyond its well-established effects on male sex characteristics, focusing on its association with non-communicable diseases (NCDs) like obesity and type 2 diabetes (T2D), using Mendelian randomization (MR) analysis on genomic data.
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