
Here the authors performed a comparative analysis to investigate the viability of using PLAY® instead of fetal bovine serum (FBS) as a growth medium to culture cells with an enzyme-linked immunosorbent assay.
Read More...An in vitro comparative analysis of the growth factors present in FBS vs PLAY®
Here the authors performed a comparative analysis to investigate the viability of using PLAY® instead of fetal bovine serum (FBS) as a growth medium to culture cells with an enzyme-linked immunosorbent assay.
Read More...Parental exposure of cannabinoids THC and CBD reduces reproductive rates in Drosophila melanogaster
The authors looked at whether CBD and THC would decrease reproductive rates in a Drosophila melanogaster model. They found that CBD had a greater impact on reducing hatching rates than THC, and that THC resulted in unexpected mortalities.
Read More...Varying levels of disinfectant resistance among invasive Klebsiella pneumoniae isolates
The authors identify disinfectant-resistant bacterial strains of infection-causing bacteria from samples collected at a hospital setting.
Read More...Apoptosis induction and anti-inflammatory activity of polyherbal drug AS20 on cervical cancer cell lines
The authors found that treatment with AS20 suppressed phorbol 12-myristate 13-acetate (PMA) and 5-flurouracil (5-FU) induction of COX2 expression. We also observed AS20 treated cells showed DNA fragmentation in HeLa cells.
Read More...Differential MERS-CoV response in different cell types
The authors compare RNA expression profiles across three human cell types following infection with MERS-CoV
Read More...Anticancer, anti-inflammatory, and apoptotic activities of MAT20, a poly-herbal formulation.
Kashyap Jha et al. look at the formulation of MAT20, a crude extract of the moringa, amla, and tulsi leaves, as a potential complementary and alternative medicine. Using HeLa cells, they find MAT20 up-regulates expression of inflammation and cell cytotoxicity markers. Their data is important for understanding the anti-cancer and anti-inflammatory properties of MAT20.
Read More...A study to determine the anti-cancer and pro-apoptotic properties of Amaranthus spinosus Linn. Extract, AS20
In this study, the authors investigate whether a new compound has anti-cancer properties. Using the crude extract from the Amaranthus spinosus plant, HeLa cancer cells were assessed for cell death. Findings reveal that the extract (AS20) has cytotoxic effects on HeLa cells. Their findings introduce a new compound to potentially pursue in the hunt for novel cancer treatments.
Read More...Using Graphene Oxide to Efficiently Filter Particulate Matter at High Concentrations
Air pollution has detrimental effects on both the environment and humans. Here, researchers use graphene oxide to filter particulate matter from the air. Graphene oxide filters performed better than commercially available filters, effectively removing particulate matter from the air.
Read More...Mechanistic deconvolution of autoreduction in tetrazolium-based cell viability assays
Optical reporters like tetrazolium dyes, exemplified by 5-diphenyl tetrazolium bromide (MTT), are effective tools for quantifying cellular responses under experimental conditions. These dyes assess cell viability by producing brightly-colored formazan dyes when reduced inside active cells. However, certain small molecules, including reducing agents like ascorbic acid, cysteine, and glutathione (GSH), can interfere with MTT assays, potentially compromising accuracy.
Read More...Pruning replay buffer for efficient training of deep reinforcement learning
Reinforcement learning (RL) is a form of machine learning that can be harnessed to develop artificial intelligence by exposing the intelligence to multiple generations of data. The study demonstrates how reply buffer reward mechanics can inform the creation of new pruning methods to improve RL efficiency.
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