In this study, the impact of fluorination of heterocyclic drug Allopurinol on its stability and other chemical properties is investigated.
Read More...A computational quantum chemical study of fluorinated Allopurinol
In this study, the impact of fluorination of heterocyclic drug Allopurinol on its stability and other chemical properties is investigated.
Read More...The impact of COVID-19 quarantine on physical activities in Basra, Iraq: A cross-sectional study
As the COVID-19 pandemic continues, the authors noticed a change in the physical activity of many people, as well as a change in the type of physical activity they practice. Here, the authors used a cross-sectional survey of 150 participants from the province of Basra in Iraq. They found an overall decrease in the number of days of physical activity for participants along with an increasing proportion of at-home exercises compared to other activities that are performed inside sports clubs during the pandemic.
Read More...A machine learning approach for abstraction and reasoning problems without large amounts of data
While remarkable in its ability to mirror human cognition, machine learning and its associated algorithms often require extensive data to prove effective in completing tasks. However, data is not always plentiful, with unpredictable events occurring throughout our daily lives that require flexibility by artificial intelligence utilized in technology such as personal assistants and self-driving vehicles. Driven by the need for AI to complete tasks without extensive training, the researchers in this article use fluid intelligence assessments to develop an algorithm capable of generalization and abstraction. By forgoing prioritization on skill-based training, this article demonstrates the potential of focusing on a more generalized cognitive ability for artificial intelligence, proving more flexible and thus human-like in solving unique tasks than skill-focused algorithms.
Read More...Using CRISPR technology to inhibit the replication of human cytomegalovirus by deletion of a gene promoter
Human cytomegalovirus (HCMV) causes serious infections in immunocompromised patients and therapies to inhibit latent HCMV are not developed. Using CRISPR/Cas9, the authors were able to delete an important promoter region in HCMV.
Read More...The effect of microplastics on the speed, mortality rate, and swimming patterns of Daphnia Magna
In this study, the authors investigate the effects that microplastics (which pollute fresh and saltwater ecosystems) have on plankton species Daphnia Magna by measuring their movement and viability.
Read More...Evaluation of Microplastics in Japanese Fish Using Visual and Chemical Dissections
Does the overuse of plastic in Japan poses an ecological risk to marine species and their consumers? Using visual and chemical dissection, all fish in this study were found to have microplastics present in their gastrointestinal tract, including two species that are typically eaten whole in Japan. Overall, these results are concerning as previous studies have found that microplastics can carry persistent organic pollutants. It is presumed that the increasing consumption of microplastics will have negative implications on organ systems such as the liver, gut, and hormones.
Read More...Overcoming The Uncanny Valley Through Shared Stressful Experience with a Humanoid Robot
The "Uncanny Valley" is a phenomenon in which humans feel discomfort in the presence of objects that are almost, but not quite, human-like. In this study, the authors tested whether this phenomenon could be overcome by sharing a stressful experience with a humanoid robot. They found that human subjects more readily accepted a robot partner that they had previously shared a stressful experience with, suggesting a potential method for increasing the effectiveness of beneficial human-robot interactions by reducing the Uncanny Valley effect.
Read More...Identification of a Free Radical Scavenger as an Additive for Lung Transplant Preservation Solution to Inhibit Coagulative Necrosis and Extend Organ Preservation
During transfer of organs from a donor to a patient, the organs deteriorate in part due to damage by free radicals. Application of antioxidant solutions could extend organ preservation times. The authors found that vitamin E and butylated hydroxytoluene seemed to be most effective in arresting cell damage of a bovine lung.
Read More...Study of neural network parameters in detecting heart disease
The authors looked at the ability to detect heart disease before the onset of severe clinical symptoms.
Read More...Associations between fentanyl usage and social media use among U.S. teens
Here the authors aimed to understand factors influencing adolescent fentanyl exposure, hypothesizing a positive association between social media usage, socioeconomic factors, and fentanyl abuse among U.S. teens. Their analysis of the Monitoring the Future dataset revealed that a history of suspension and use of marijuana or alcohol were linked to higher fentanyl use, and while not statistically significant, a notable positive correlation between social media use and fentanyl frequency was observed.
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